BookMarkus Hecker, Dirk J. Duncker, editors.
Summary: This volume of the series Cardiac and Vascular Biology presents the most relevant aspects of vascular mechanobiology along with many more facets of this fascinating, timely and clinically highly relevant field. Mechanotransduction, mechanosensing, fluid shear stress, hameodynamics and cell fate, are just a few topics to name. All important aspects of vascular mechanobiology in health and disease are reviewed by some of the top experts in the field. This volume, together with a second title on cardiacmechanobiology featured in this series, will be of high relevance to scientists and clinical researchers in the area of vascular biology, cardiology and biomedical engineering.
Contents:
Preface
Hemodynamics and vascular remodeling
The biomechanics of venous remodeling
New kids on the block: the emerging role of YAP/TAZ in vascular cell mechano-transduction
GPCRs und flow and pressure
Biomechanics in small artery remodeling
Contributions of wall stretch and shear stress to vascular regulation: Molecular mechanisms of homeostasis and expansion
Mechanobiology of lymphatic vessels
Hemodynamic control of endothelial cell fates in development
Mechanical regulation of epigenetic modifications in vascular biology and pathobiology
Mechanosensing and mechanotransduction in pulmonary hypertension
Mechanobiology of arterial hypertension
Mechanobiology of atherosclerosis
Exploitation of vascular mechanobiology for cardiovascular therapy.