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  • Book
    Mohamed Fawzy Ramadan, editor.
    Summary: Recent developments in the field of nutrition have led to increased interest in herbs and medicinal plants as phytochemical-rich sources for functional food, nutraceuticals, and drugs. As research sheds light on the therapeutic potential of various bioactive phytochemicals, the demand for plant extracts and oils has increased. Black cumin or black seeds (Nigella sativa) have particularly widespread nutritional and medicinal applications. In traditional medicine, black seeds are used to manage fatigue and chronic headache. Black seed oil is used as an antiseptic and analgesic remedy and for treatment of joint's pain and stiffness and can be mixed with sesame oil to treat dermatosis, abdominal disorders, cough, headache, fever, liver ailments, jaundice, sore eyes, and hemorrhoids. Thymoquinone, the main constituent in black seed volatile oil, has been shown to suppress carcinogenesis. Black cumin (Nigella sativa) seeds: Chemistry, Technology, Functionality, and Applications presents in detail the chemical composition, therapeutic properties, and functionality of high-value oils, phytochemicals, nutrients, and volatiles of the Nigella sativa seed. Organized by formulation (seeds, fixed oil, essential oil, and extracts), chapters break this seed down into its chemical constituents and explore their role in the development of pharmaceuticals, nutraceuticals, novel food, natural drugs, and feed. Following numerous reports on the health-promoting activities of Nigella sativa, this is the first comprehensive presentation of the functional, nutritional, and pharmacological traits of Nigella sativa seeds and seed oil constituents.

    Contents:
    1. Introduction to black cumin (Nigella sative): Chemistry, Technology, Functionality and Applications
    Section 1. Nigella sative seeds: Cultivation, Composition and Applications
    2. Effect of cultivation, fertilization and irrigation practices on Nigella sative yield and quality
    3. Morphological characters of Nigella sativa
    4. Micro and macroscopic characterization of traded Nigella sativa seeds using applied systematics techniques
    5. Composition of Nigella sativa seeds
    6. Nigella sativa seed peptides (Thionins)
    7. Black cumin polysaccharides
    8. Thymoquinone: Chemistry and cunctionality
    9. Novel Prospective of Nigella sativa Essential Oil Analysis, Culinary and Medicinal Uses
    10. Rediscovering Nigella Seeds Bioactives Chemical Composition using Metabolomics Technologies
    11. Health promoting activities of Nigella sativa seeds
    12. Nigella sativa seed extract in green synthesis and nanocomposite
    13. Food applications of Nigella sative seeds
    14. Nutraceutical importance and applications of Nigella sativa seed flour
    15. Nigella sativa seed cake: nutraceutical significance and applications in the food and cosmetic industry
    16. Nigella sative seeds in cosmetic products
    17. Nigella sativa supplementation in ruminant diets: production, health, and environmental perspectives
    18. Nigella sativa seeds and its derivatives in poultry feed
    19. Nigella sative Seeds and Its Derivatives in Fish Feed
    Section 2: Nigella sative fixed oil: Chemistry, Technology, Functionality and Applications
    20. Composition and Functionality of Nigella sativa Fixed Oil
    21. Effect of processing on the composition and quality of Nigella sativa fixed oil
    22. Food applications of Nigella sativa Fixed Oil
    23. Health-Promoting Activities of Nigella sativa Fixed Oil
    24. Micro- and Nano-encapsulation of Nigella sativa Oil
    25. Biodiesel Production Potential of Nigella sativa Oil
    Section 3: Nigella sative essential oil: Chemistry, Technology, Functionality and Applications
    26. Composition and functionality of Nigella sativa essential oil
    27. Effect of processing on the composition and quality of Nigella sativa essential oil
    28. Food applications of Nigella sativa essential oil
    29. Health-promoting activities of Nigella sativa essential oil
    Section 4: Nigella sative seed extracts: Chemistry, Technology, Functionality and Applications
    30. Composition and Functionality of Nigella sativa Seed Extracts
    31. Nigella sativa seed extracts in functional foods and nutraceutical applications
    32. Health promoting activities of Nigella sativa seed extracts.
    Digital Access Springer 2021
  • Article
    Tonooka N, Leslie GA, Greer MA, Olson JC.
    Am J Pathol. 1978 Sep;92(3):681-90.
    Severe lymphoid thyroiditis and associated hypothyroidism occurred in all of 7 male and 4 female F(7) derivatives (seventh generation) of rats immunized in each generation against Group A streptococci. This evidence of thyroiditis produced by immunization against a nonthyroidal antigen suggests that some cases of Hashimoto's thyroiditis in humans may result from nonspecific immune responses.
    Digital Access Access Options