BookSatoshi Kuroda, editor.
Summary: This book brings together the latest knowledge on moyamoya disease, covering diagnostic criteria, status as a disease entity, genetic aspects, pathophysiology, novel neuroradiological findings, and surgical therapy. Information is also provided on recent basic and clinical research with the aim of identifying future perspectives on the disease. Since moyamoya disease was first reported in an English language article more than 50 years ago, our understanding of it has advanced considerably. Genetic and radiological analysis has delivered novel insights, and the latest multicenter studies are changing routine diagnosis and surgical therapy. The gene encoding the ring finger protein 213 (RNF213) has been identified as a susceptibility gene for moyamoya disease. Indications and procedures for surgical revascularization have been revised, with resultant improvements in outcomes, and studies performed over the past decade have provided new knowledge on the neuroradiological findings before and after surgery. In describing these advances, this book will be an invaluable asset for all general physicians, pediatricians, neurologists, radiologists, and neurosurgeons who care for patients with moyamoya disease across the world.
Contents:
Part I Concept of Moyamoya Disease
1 History of Disease Entity & Diagnosis Criteria
2 Moyamoya Syndrome
3 Unilateral Moyamoya Disease: A Distinct Entity?
Part II Genetic Aspect of Moyamoya Disease
4 RNF213 as Susceptibility Gene
5 RNF213 and clinical feature
6 RNF213 Variant as a Biomarker of Cerebrovascular Disease
Part III Pathophysiology of Moyamoya Disease
7 TIA & Headache in Pediatric Moyamoya Disease
8 Ischemic stroke
9 Hemorrhagic Stroke and the Japan Adult Moyamoya Trial
10 Cognitive Function in Pediatric Moyamoya Disease
11 Cognitive Dysfunction in Adults
12 Asymptomatic Moyamoya Disease
Part IV Update on Neuroradiology in Moyamoya Disease
13 Periventricular Anastomosis
14 Arterial Shrinkage
15 Disease progression
16 Postoperative hyperperfusion
17 Postoperative FLAIR Imaging Changes
Part V Real World of Surgical Revascularization for Moyamoya Disease
18 Overview of Surgical Revascularization and Long-term Outcome in Japan
19 Perioperative complications
20 Long-term Outcome in Europe
21 Long Term Outcomes in USA
22 Long-term Outcome in China
23 Long-term outcome of revascularization surgery for moyamoya disease in Korea
24 Indirect bypass surgery for moyamoya disease
25 Direct/combined bypass surgery
26 Special Considerations--Infants
27 Special Considerations
Elderly.