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  • Book
    Gabriel I. Uwaifo, editor.
    Summary: The hypothalamus is an anatomically small but functionally important part of the brain. In functional and pathophysiological terms, the hypothalamus represents the intersection of several areas of clinical and medical expertise. The human hypothalamus can be astutely referred to as the crossroad of endocrinology, psychiatry, neurology and neurosurgery. Because of its involvement in myriad physiologic functions and the varied ways disorders involving it can manifest, hypothalamic disease can initially come to medical attention in widely disparate settings and with widely different clinicians. Therefore, the detection and proper care of hypothalamic dysfunction and disease often requires carefully coordinated multidisciplinary care. This volume fills a significant void in the medical professional community, comprehensively presenting the scope of hypothalamic structure, function, dysfunction and disease to cater to the various clinical, teaching and research professionals that have a stake in this part of the human brain. This text captures in one place all the information that practicing clinicians, clinician scientists, and researchers need to be adequately informed about various aspects of the hypothalamus in all its complexity. It is comprehensive and broad in scope so that it provides relevant reference information for the wide range of professionals involved in the pre- and post-mortem detection, diagnosis, characterization, care and management of various hypothalamic disorders and diseases in addition to providing a sound anatomic and physiologic foundation of the normal human hypothalamus. The Human Hypothalamus can be used to differing degrees by medical professionals and students alike, finding utility for interested general clinicians, medical school and allied health professional teaching faculty as well as subspecialists in domains as wide as neurosurgery, neuroendocrinology, clinical psychiatry and neuro-oncology.

    Contents:
    Part I: Structure and Function of the Hypothalamus
    Introduction to the Hypothalamus: Correlates from Animal Studies
    Anatomy and Topography of the Hypothalamus
    Neuroimaging of the Hypothalamus
    Neurophysiology of the Hypothalamus
    Neuroendocrinology of the Hypothalamic-Pituitary-Adrenal Axis
    Part II: Pathobiology and Dysfunction of the Hypothalamus
    Neuropsychiatric, Neurologic, and Neurobehavioral Syndromes of the Hypothalamus
    Neurosurgical Aspects of Hypothalamic Disease
    Hormone Excess Syndromes of the Hypothalamic-Pituitary-Adrenal Axis
    Hormone Deficiency Syndromes of the Hypothalamic-Pituitary-Adrenal Axis
    Hypothalamic Obesity and Wasting Syndromes
    Hypothalamic Sleep Disorders
    Genetic Syndromes of Hypothalamic Dysfunction
    Neuroendocrine Tumors of the Hypothalamus
    Non-endocrine Tumors of the Hypothalamus
    Non-neoplastic Mass Lesions of the Hypothalamus
    Rapid-onset Obesity with Hypothalamic Dysregulation, Hypoventilation, and Autonomic Dysregulation (ROHHAD) and ROHHAD Association Syndromes
    Infectious and Inflammatory Hypothalamic Diseases
    Traumatic and Degenerative Hypothalamic Diseases
    Iatrogenic Hypothalamic Diseases
    Idiopathic Diseases of the Hypothalamus.
    Digital Access Springer 2021
  • Article
    Podolsky S.
    Med Clin North Am. 1978 Jul;62(4):815-28.
    The gravity of this syndrome of severe diabetic stupor without ketosis may not be recognized because patients are usually middle-aged or elderly with mild diabetes. A lack of urgency in treating these patients is probably the cause of the widely reported mortality of 40 to 70 per cent.
    Digital Access Access Options