BookSantiago Horgan, Karl-Hermann Fuchs, editors.
Summary: This book provides a comprehensive state-of-the-art overview on the established knowledge in the field of gastroesophageal reflux disease (GERD) as well as a current insight into new algorithms involving new diagnostic tools and new endoscopic and surgical techniques. The integration of these new findings in updated therapeutic decision making is demonstrated. The book reviews the latest literature on new diagnostic findings to better discriminate between different benign disorders of the esophagus and stomach. It describes the decision making to establish indications for the variety of established and new therapeutic options in the management of the disease. It also describes in detail new therapeutic techniques, which provides excellent back-up information for every clinician in daily practice. Management of Gastroesophageal Reflux Disease is a valuable resource for clinicians, surgeons, nurses, technicians, students and researchers with an interest in esophageal and upper GI- disease.
Contents:
Intro
Foreword
Contents
Contributors
1: Definition and Pathophysiology of Gastroesophageal Reflux Disease
Introduction and Definition
The Anatomy of the Esophagus and Stomach
Pathophysiology of GERD
The Incompetence of the LES
The Transient Lower Esophageal Sphincter Relaxations (TLESRs)
Histopathologic Considerations
Pathophysiologic Overview and Summary
References
2: Symptom Spectrum in Gastroesophageal Reflux Disease
Introduction
Diagnostic Workup for Patients with Symptoms Indicative of GERD
The Variety of Symptoms in Patients with GERD Symptom Profile of Esophageal Motility Disorders
GERD Symptoms and Somatoform Disorders
Conclusion
References
3: Diagnostic Investigations in GERD
Introduction
Diagnostic Investigations
Endoscopy
Radiographic Investigations
Impedance-pH Monitoring
High-Resolution Manometry (HRM)
Conclusion
References
4: Medical Therapy of GERD
Introduction
Lifestyle Intervention in GERD
Medical Therapy
Safety of PPI Therapy
Problems with PPI Therapy
References
5: Indications for Interventional and Surgical Therapy in GERD Basic Considerations for Alternative Options to Medical Therapy
Indication for Antireflux Surgery
Indications for Antireflux Surgery in Special Circumstances
Indication for Surgery in the Elderly
Indication for Antireflux Surgery in Patients with NERD (Nonerosive Reflux Disease)
Indication for Antireflux Surgery in Patients with Extra-Esophageal Symptoms
Indication for Antireflux Surgery in Patients with Delayed Gastric Emptying
References
6: Endoscopic Therapy for GERD
Introduction
Indications and Contraindications
Technical Aspects of Currently Available EART Endoscopic Full-Thickness Plication
Radiofrequency Ablation
Endoscopic Mucosa Resection
Clinical Evidence for EART
Endoscopic Fundoplication
Radiofrequency Ablation
Endoscopic Mucosa Resection
Complications
Summary
References
7: Surgical Management of Gastroesophageal Reflux Disease
Indications
Preoperative Evaluation
Operative Procedures
Nissen Fundoplication
Partial Fundoplication
Belsey Mark IV Fundoplication
Magnetic Sphincter Augmentation
Endoscopic Methods
Gastric Bypass
Comparative Outcomes
Conclusion
References 8: The Nissen Fundoplication
Introduction
The Principle of Action of a Nissen Fundoplication
Operative Technique
Special Issues
Results of Laparoscopic Nissen Fundoplication
Conclusion
References
9: The Posterior Partial Toupet Hemifundoplication
Introduction
Operative Technique
Special Issues About the Partial Fundoplication
Results of Partial Toupet Hemifundoplication
Conclusion
References
10: Controversies Regarding Mesh Implantation for Hiatal Reinforcement in GERD and Hiatal Hernia Surgery
Introduction
Basic Pathophysiology of Hiatal Hernias