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  • Book
    Romesh Kumar Salgotra, Sajad Majeed Zargar, editors.
    Summary: This book describes how the latest genomic resources techniques can be efficiently used in plant breeding programmes to achieve food security in the future. It also shares insights on how to utilize the untapped and unexplored genetic diversity of wild species, wild relatives and landraces for crop improvement. Moreover, the book offers an impressive array of balanced analyses, fresh ideas and perspectives, and thoughtful and realistic proposals regarding the sustainable utilization of plant genetic resources with modern biotechnological techniques. The first book to address the importance of plant genetics and genomic resources for food security, it brings together a group of plant breeders and biotechnologists to investigate the use of genomic resources techniques in plant breeding programmes. Providing essential information on the efficient utilization of genomic resources in precision breeding, it offers a valuable asset for undergraduate and graduate students, teachers and professionals engaged in related fields.

    Contents:
    Chapter 1 Potential of genetic and genomic resources for genetic improvement of food crops
    Chapter 2 Untapped genetic diversity of wild relatives for crop improvement
    Chapter 3 Molecular approaches for harvesting natural diversity for crop improvement
    Chapter 4 Omics and plant genetic resources: Towards mining potential genes
    Chapter 5 Genetic and genomic resources and their exploitation for unlocking genetic potential from the wild relatives.-Chapter 6 Role of gene banks in maintaining crop genetic resources
    Chapter 7 Exploring genetic resources for identification of potential novel genes for crop improvement
    Chapter 8 Next-generation sequencing technologies and their implications for efficiently utilization of genetic resources
    Chapter 9 Comparative genomics for exploring new genes and traits for crop improvement
    Chapter 10 Potential of wild species in the scenario of climate change
    Chapter 11 Role of wild relatives for development of climate-resilient varieties
    Chapter 12 Strategies for conservation of genetic resources
    Chapter 13 Crop landraces: Present threats and opportunities for conservation
    Chapter 14 Future threats and opportunities facing crop wild relatives and landrace diversity.
    Digital Access Springer 2020
  • Article
    Valdivieso M, Mavligit GM.
    Surg Clin North Am. 1978 Jun;58(3):619-31.
    The current status of treatment for patients with colorectal cancer is suboptimal. Although approximately 80% of patients are amenable to surgery, cure is only possible for 40%. Survival of patients is closely related to disease staging at the time of surgery, being poorer for patients presenting with locally advanced disease or with distant metastases. Patients who undergo curative resections and are categorized as having a high risk of developing recurrence, such as those with regionally involved lymph nodes, should be subjected to studies of adjuvant therapy. Although the definite role of such studies is still under evaluation, there already exist studies of chemotherapy with 5FU, chemoimmunotherapy with 5FU-BCG, and radiation therapy, suggesting the beneficial effect of these treatment modalities based on prolongation of the disease-free interval and survival of patients. The status of available treatments for patients with advanced disease is poor. There exists no single or multidrug regimen capable of producing significant tumor regression to improve the patient's quality of life and survival. Accordingly, the active clinical investigation of newer and potentially effective chemotherapeutic agents should continue. The role of present immunotherapy is not fully determined, although several studies suggest its potential usefulness in the adjuvant and the advanced situations. Serial determinations of CEA are extremely helpful in the postsurgical monitoring of patients receiving adjuvant treatments and also in the follow-up of patients undergoing therapy for overt metastatic disease.
    Digital Access Access Options