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  • Book
    Karam B. Singh, Lars G. Kamphuis, Matthew N. Nelson, editors.
    Summary: This book on lupin genomics primarily focuses on the narrow-leafed lupin (NLL), and details the genomic resources that have been developed and how they are currently being used to help advance both fundamental and applied research on NLL in areas ranging from its domestication to plant-microbe interactions and syntenic relationships between NLL and other legume crops. It also reports on genomic efforts being pursued with regard to other lupin crops. Lupins are important ecological 'engineers': they can colonise and thrive in low-nutrient soils due to their ability to fix atmospheric nitrogen in symbiosis with bacteria and efficiently take up phosphorous. Recently, lupins have attracted considerable interest, not only because of their value for sustainable farming as a break crop, but also as a potential 'super food' for fighting major health issues in connection with diabetes and obesity. Narrow-leafed lupin is the main grain legume crop, grown primarily in Australia, and was therefore selected for the development of a reference lupin genome and associated genomic resources. Its genome has recently been sequenced with a focus on the gene-rich space, which has advanced the development of new breeding tools for the improvement of NLL and related lupin crops.

    Contents:
    Introduction to lupins and their importance
    Lupin breeding
    lessons from the past and prospects for the future
    Ecophysiology and genetic resources for genetic/genomic improvement of NLL
    NLL reference genome
    Cytomolecular insight into/Lupinus/ genomes
    NLL transcriptomics
    Molecular marker resources
    Targeted towards Australian breeding program
    Syntenic relationships between NLL and other legume crops
    Exploiting NLL genomic resources to understand NLL domestication
    Genomic applications to dissect plant-microbe interactions
    Genomic applications to dissect flowering time control in NLL
    GBS-based genomic selection in white lupin
    Genomic efforts for L. luteus
    L. mutabilis genome and associated evolutionary analyses
    Genomic efforts to analyse repetitive elements in lupin species.
    Digital Access Springer 2020
  • Article
    Schwarz R.
    Psychiatr Neurol Med Psychol (Leipz). 1978 Apr;30(4):192-208.
    The paper gives a survey on the results of research on etiology and course of schizophrenia. The results of etiological research have not, as yet, progressed so far as to provide measures of primary prevention, whereas the results of research into the course of schizophrenia have already led to practical consequences for therapy resp. rehabilitation of schizophrenic patients. In future, with a decrease in the number of long-stay hospitalizations, the number of schizophrenic out-patients, resp. of prolonged periods of out-patient treatments will increase accordingly. Thus hitherto known influencing factors and treatment strategies will also be due to change. According to present knowledge, etiology, psychopathology, course and outcome of schizophrenia represent a very complex and variable, multifactorially initiated process, in which illness-related and environment-related factors concur. Drafts of new models and instruments for the assessment of this process and subsequent disabilities as well as methodological difficulties herewith are reported.
    Digital Access Access Options
  • Book
    Print v. 1, pt. 1-16; Nov. 1935-Sept. 1947.