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  • Book
    Digital Access Springer 2020
  • Article
    Kitai K, Arakawa A.
    Poult Sci. 1978 Mar;57(2):392-7.
    The in vitro activity of six different antimicrobial agents was evaluated by an agar dilution method against enteric bacteria isolated from broilers. Of 923 isolates, 796 were gram-positive bacteria and 127 were Escherichia coli (E. coli). Thiopeptin at 25 microgram/ml inhibited 75% of lactobacilli. This antibiotic at .78 microgram/ml inhibited 82% of staphylococci and more than 92% of other gram-positive organisms. Bacitracin at 100 microgram or less per ml was active against 42% of staphylococci and 30% of streptococci. At 6.25 microgram or less per ml, 70% of clostridia and 78% of lactobacilli were inhibited. The minimum inhibitory concentrations (MIC) of penicillin G and ampicillin shown as cumulative distribution curves for all isolates were very similar. Both antibiotics showed a wide range of MIC distribution. Streptomycin at 50 microgram or less per ml was active against 87% of lactobacilli and 50% of E. coli. Only 32% of staphylococci were inhibited at these concentrations. At 100 microgram or less per ml, 30% of streptococci and 12% of clostridia were inhibited. Tetracycline at 100 microgram or less per ml inhibited 63% of clostridia. Lactobacilli and E. coli were not inhibited by this antibiotic at 100 microgram or less per ml.
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