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  • Book
    by Xiangbin Pan, Ziyad M. Hijazi, Horst Sievert.
    Summary: This book provides an extensive discussion of echocardiography-guided percutaneous interventional techniques for clinical practitioners, including cardiologists, interventional physicians, surgeons and specialist training candidates. It allows readers to gain a thorough understanding of interpreting echocardiography-guided procedures, which not only protect patients from pain and other complications associated with conventional surgery, but also obviate the use of fluoroscopy or contrast agents and so avoid radiation damage and the risks of allergy or renal function impairment. Further, these procedures could help to save patients in areas lacking medical resources. The book first demonstrates the substitution of transesophageal for transthoracic echocardiography to avoid intubation under general anesthesia, and then presents key technical and practical aspects of echo-guided percutaneous interventions for structural heart diseases, such as ASD, VSD, PDA, PS, MS, AS and CoA. Lastly, it explores the lessons learned in echocardiography, anesthesia and postprocedural management of echo-guided percutaneous interventions.

    Contents:
    Introduction
    Anesthesia Management in Echocardiography-guided Percutaneous Interventions for Structural Heart Disease
    Use of Echocardiography in Percutaneous Interventions for Structural Heart Disease
    Echocardiography-guided Interventional Atrial Septal Defect Closure
    Echocardiography-guided Interventional for Pulmonary Stenosis
    Echocardiography-guided Interventional Patent Ductus Arteriosus Closure
    Echocardiography-guided Interventional Closure of Perimembranous Ventricular Septal Defect
    Echocardiography-guided Interventional Left Atrial Appendage Closure
    Echocardiography-guided Percutaneous Interventional for Mitral Valve Stenosis
    Echocardiography-guided Percutaneous Interventional for Aortic Valve Stenosis
    Echocardiography-guided Percutaneous Interventional for Coarctation of Aorta
    Post-procedural Management of Echocardiography-guided Percutaneous Interventions.
    Digital Access Springer 2020
  • Article
    Buhles WC, Shifrine M.
    Infect Immun. 1978 Apr;20(1):58-65.
    The effects of complete Freund adjuvant (CFA) or Mycobacterium bovis BCG on leukopoiesis and on leukopoietic recovery from cyclophosphamide treatment in mice was studied. CFA injected subcutaneously or intraperitoneally resulted in increased blood granulocyte and monocyte counts, increased numbers of bone marrow granulocyte and mononuclear phagocyte progenitors, and increased hematopoietic colony-stimulating factor in the serum. Furthermore, the quantitative cellular response within 24 h to an induced sterile intraperitoneal inflammation (thioglycolate) was augmented by subcutaneous CFA. In mice given CFA subcutaneously, blood granulocyte counts, as well as the peritoneal granulocyte and macrophage response to intraperitoneal thioglycolate, recovered more quickly than did those of the controls after a 250-mg/kg dose of cyclophosphamide. CFA-treated mice consistently maintained blood granulocyte and monocyte counts 1.3-to 4-fold higher than those of the controls for 2 weeks while receiving 75 mg of cyclophosphamide per kg every other day. Mice pretreated with CFA intraperitoneally had higher numbers of bone marrow colony-forming units in culture and higher levels of serum colony-stimulating factor after 250-mg/kg injections of cyclophosphamide. Similarly, BCG resulted in increased bone marrow colony-forming units in culture, increased serum colony-stimulating factor, and a faster return of the peritoneal inflammatory response after cyclophosphamide injection. These results show that mycobacterial adjuvants accelerate recovery of leukopoietic functions after cyclophosphamide treatment and suggest a mechanism whereby such adjuvants afford nonspecific protection against infection in immunosuppressed mice.
    Digital Access Access Options