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  • Book
    editors, Charlotte Lindqvist and Om P. Rajora.
    Summary: Advances in genome-scale DNA sequencing technologies have revolutionized genetic research on ancient organisms, extinct species, and past environments. When it is recoverable after hundreds or thousands of years of unintended preservation, "ancient DNA" (or aDNA) is often highly degraded, necessitating specialized handling and analytical approaches. Paleogenomics defines the field of reconstructing and analyzing the genomes of historic or long-dead organisms, most often through comparison with modern representatives of the same or similar species. The opportunity to isolate and study paleogenomes has radically transformed many fields, spanning biology, anthropology, agriculture, and medicine. Examples include understanding evolutionary relationships of extinct species known only from fossils, the domestication of plants and animals, and the evolution and geographical spread of certain pathogens. This pioneering book presents a snapshot view of the history, current status, and future prospects of paleogenomics, taking a broad viewpoint that covers a range of topics and organisms to provide an up-to-date status of the applications, challenges, and promise of the field. This book is intended for a variety of readerships, including upper-level undergraduate and graduate students, professionals and experts in the field, as well as anyone excited by the extraordinary insights that paleogenomics offers.

    Part1. Concepts, Technical Advances and Challenges
    Chapter1. Technical Advances and Challenges in Genome-Scale Analysis of Ancient DNA
    Chapter2. Paleoproteomics: An Introduction to the Analysis of Ancient Proteins by Soft Ionization Mass Spectrometry
    Chapter3. Ancient RNA
    Chapter4. Ancient Epigenomics
    Chapter5. Ancient Pathogens Through Human History: A Paleogenomic Perspective
    Chapter6. Paleovirology: Viral Sequences from Historical and Ancient DNA
    Chapter7. Reconstructing Past Vegetation Communities Using Ancient DNA from Lake Sediments
    Chapter8. Archaeogenomics and Crop Adaptation
    Chapter9. Herbarium Genomics: Plant Archival DNA Explored
    Chapter10. Paleogenomics of Animal Domestication
    Chapter11. Paleogenomic Inferences of Dog Domestication
    Chapter12. Of Cats and Men: Ancient DNA Reveals How the Cat Conquered the Ancient World
    Chapter13. An Ancient DNA Perspective on Horse Evolution
    Chapter14. Primate Paleogenomics
    Chapter15. Structural Variants in Ancient Genomes
    Chapter16. Genomics of Extinction.
    Digital Access Springer 2019