BookAndrzej Górski, Ryszard Miȩdzybrodzki, Jan Borysowski, editors.
Summary: This book gives a detailed yet clear insight into the current state of the art of the therapeutic application of bacteriophages in different conditions. The authors bring in their practical expertise within their respective fields of expertise and provide an excellent overview of the potential and actual use of phage therapy. Topics like economic feasibility compared to traditional antibiotics and also regulatory issues are discussed in far detail. This new volume is therefore a valuable resource for individuals engaged in the medical application of novel phage therapies.
Contents:
Part I: Bacteriophages as antibacterialagents
Chapter 1:Production of PhageTherapeutics and Formulations
InnovativeApproaches
Chapter 2:Phagepharmacokinetics: relationship with administrationroute
Chapter 3:BacterialResistance to Phage and itsImpact on Clinical Therapy
Part II: Bacteriophages and the immune system
Chapter 4:Phageinteraction with the mammalianimmune system
Chapter 5:Humoralimmuneresponse to phage-basedtherapeutics
Part III:Use of bacteriophages to combat bacterial infections
Chapter 6:How to achieve a goodphage therapy clinical trial?
Chapter 7: Perspectives on the RenewedInterest in the United States
Chapter 8:Phage Therapy in Orthopaedic Implant-associated Infections
Chapter 9:The use of bacteriophages in animalhealth and food protection
Chapter 10:Combiningbacteriophages with otherantibacterialagents to combatbacteria
Chapter 11: Phage therapy of infectious biofilms: Challenges and strategies
Part IV:Phage therapy
regulatory and ethical aspects
Chapter 12:Regulatory Considerations for Bacteriophage Therapy Products
Chapter 13:Developing phagesintomedicines for Europe
Chapter 14: Phagetherapy in Europe: Regulatory and intellectualpropertyprotectionissues
Chapter 15:Ethics of phagetherapy
Part V: Bacteriophage-derived antibacterial agents
Chapter 16: NovelAlternative to Antibiotics.