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  • Book
    Wang Jae Lee.
    Summary: This book presents the scientific evidence for the role of vitamin C in health and disease and offers new guidance on vitamin C intake in humans. The importance of vitamin C in preventing cancer and cardiovascular disease, its relevance to aging and stress, and its impacts on each of the human body systems are thoroughly assessed on the basis of the authors extensive research and his deep understanding, as an anatomy professor, of the body as a whole. Findings published in the international scientific literature are fully taken into account, and due consideration is also given to empirical evidence, bearing in mind that mechanisms of action cannot always be precisely defined in the absence of human experiments. Beyond providing an up-to-date scientific perspective on the effects of vitamin C, the author hopes to promote human health worldwide by encouraging proper use of the vitamin. To this end, recommendations are made on the amount of vitamin C that should be taken daily and on the best way to take it. The book will be of interest to researchers, clinicians, and all others who wish to learn more about this vitamin and its significance.

    Contents:
    Intro; Preface; Contents;
    Chapter 1: Introduction; History of Vitamin C Discovery; What Is Vitamin C?; Brief Explanation of the Biochemical Properties of Vitamin C; Copenhagen Report; Other Biological Activities of Vitamin C Besides Its Roles as an Antioxidant; Sodium-Dependent Vitamin C Transporters (SVCTs); Pharmacokinetics of Vitamin C; Scientific Background on the Recommended Daily Allowance (RDA) of Vitamin C; How to Take Vitamin C; Adverse Effects of Vitamin C; References;
    Chapter 2: Cardiovascular System; Cardiovascular System; Heart; Arteries and Veins; Blood Pressure Atherosclerotic Vascular DiseasesPathogenesis of Atherosclerotic Disease; Vitamin C and Nitric Oxide (NO); French Paradox; Scientific Background on the Potential Beneficial Effects of Vitamin C on the Prevention of Atherosclerotic Vascular Diseases; Review of Epidemiological Studies on Relationship Between Vitamin C and Atherosclerotic Vascular Diseases; Relation Between the Plasma Vitamin C Level and Atherosclerotic Vascular Diseases; Relation Between Oral Intake of Vitamin C and Atherosclerotic Diseases Hints from Worldwide Longevity VillagesReferences;
    Chapter 8: Stress; Body Responses to Stress; Role of Vitamin C in the Production of the Stress Hormones; Stress and Health; Utilization of Stress; Vitamin C and Disease and Death; References;
    Chapter 9: Digestive System; Gastrointestinal (GI) Tract; Associated Digestive Glands; Nitrosamine, a Possible Carcinogen, H. pylori, and Vitamin C; SVCT1 and Small Intestine; The Colon and Vitamin C; Vitamin C and Acute Pancreatitis; References;
    Chapter 10: Liver; Blood Supply System to the Liver; Liver and Immune System; Vitamin C and Liver Diseases Role of Vitamin C in the Protection of Blood Vessels from Damage by Exercise for Health PromotionReferences;
    Chapter 3: Cancer; Causes of Cancer Formation; Treatment Modalities for Cancer; Review of the Anticancer Effects of Vitamin C; Mechanisms Involved in Tumor Cell Killing by Vitamin C; Suggestions; References;
    Chapter 4: Immune System; Non-specific Immune System; Specific Immune System; Link Between the Innate and Adaptive Immune Systems; Vitamin C and B Lymphocytes; Vitamin C and T Lymphocytes; Vitamin C and NK Cells; Vitamin C and Other Immune Cells Involved in Innate Immunity
    Digital Access Springer 2019
  • Article
    Cendrowski W, Członkowska A.
    Acta Neurol Scand. 1978 Apr;57(4):354-9.
    Nineteen patients with multiple sclerosis (MS) have been given one course of levamisole therapy, and 16 patients two courses of levamisole treatment in daily dosages of 100--150 mg over two periods lasting from 1 month to 22 weeks each. Clinical effect was evaluated using Kurtzke's disability status scale. Immediate clinical evaluation showed that 15 patints remained unchanged, two improved and two became worse. Follow-up revealed after 4--14 months that another four patients deteriorated and none improved. Altogether 10 patients developed 13 relapses. During this brief therapy, no convincing conclusions may be drawn regarding an influence upon the course of the disease, although there is the suggestion that levamisole was not beneficial in MS patients. There was no statistically significant effect of levamisole on peripheral blood lymphocyte count, lymphocyte stimulation tests, leucocyte migration inhibition tests, short and long incubation E-rosette forming cells and serum IgA, IgG or IgM levels. A group of MS patients showed after 1 month of levamisole treatment either short-lasting restored or potentiated skin hypersensitivity to bacterial and fungal antigens (P less than 0.05).
    Digital Access Access Options