Today's Hours: Closed
Lane Medical Library

Search

Filter Results

Did You Mean:

Search Results

Sort by
relevance
  • Book
    Alexzander A.A. Asea, Punit Kaur, editors.
    Summary: This edited volume offers an insightful overview of contemporary research on signaling pathways. These signaling processes are the comprehensive mechanisms by which all cellular organisms communicate internally and externally with their microenvironment. The volume is focused on heat shock proteins (HSP), which are uniquely involved in a number of critical signaling pathways. Errors in signaling pathways and in the processing of cellular information are known to be responsible for the majority of diseases including cancer, inflammatory and neurological disorders. The knowledge gained from better understanding these mechanisms can help in elucidating disease processes and will assist in development and design of novel targeted treatment therapies to combat human diseases and disorders. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.

    Contents:
    Thiol-based Redox Signaling: Impacts on Molecular Chaperones and Cellular Proteostasis
    Heat Shock Proteins (HSP) in Stress-Related Inflammatory Diseases
    Heat Shock Response and Metabolism in Skeletal Muscle
    Temperature Stress and Redox Homeostasis: The Synergistic Network of Redox and Chaperone System in Response to Stress in Plants
    Dynamics of Heat Shock Proteins in Immunity and Aging
    Heat Shock Proteins, Exercise and Inflammation
    Heat Shock Proteins and Alarmins in Autoimmunity
    HO-1/Hsp32 and Cardiac Stress Signaling
    Targeting Heat Shock Proteins in Multiple Myeloma
    IER5 is a p53-Reguated Activator of HSF1 that Contributes to Promotion of Cancer
    Heat Shock Proteins in Digestive Tract Cancer: Molecular Mechanism and Therapeutic Potential
    The Role of Heat Shock Protein 90 in Regulating Downstream Signal Transduction Cascades
    Extracellular Hsp90a versus Intracellular Hsp90b in Wound Healing and Cancer
    Regulation of Calcineurin Signaling through Blocking of the Chaperone Function of Hsp90 by HDAC Inhibitors
    Signaling Functions of Extracellular Hsp90 (eHsp90) in Cancer Metastasis
    The Role of the Molecular Chaperones Hsp70 and Hsp90 in the DNA Damage Response
    Heat Shock Protein 90 Inhibitors in Lung Cancer Therapy
    Hsp90 Inhibitors Blocking Multiple Oncogenic Signaling Pathways for the Treatment of Cancer
    Diverse Roles of Heat Shock Proteins in Immune Activation and Tolerance: A Comprehensive Review of Mechanisms and Therapeutic Relevance
    The Role of Heat Shock Proteins on Neuromuscular Disorders/Neuronal Differentiation
    Heat Shock Proteins in Neural Signaling: Implications in Health and Disease
    Cytosolic Heat Shock Protein 90 in Plant Hormone and Environmental Stress Response.
    Digital Access Springer 2019
  • Article
    Peddie BA, Little PJ.
    Zentralbl Bakteriol Orig A. 1978 Apr;240(3):320-5.
    525 isolates of E. coli were obtained from the urine of patients during episodes of urinary tract infection (UTI). Of these, 250 cultures were from asymptomatic patients, detected during screening of adolescent or pregnant women. The remaining 275 cultures were from patients who attended general practitioners with symptoms of UTI. When isolates were typed using commercial urinary E. coli O antisera, 39.2% from asymptomatic UTI and 32.4% from symptomatic UTI were non-typable. There were 29.2% autoagglutinating isolates from asymptomatic and 14.5% from symptomatic UTI. The most frequently isolated O serogroups were O6, O75 and O18. Numbers of O6 and O75 were higher in symptomatic UTI than asymptomatic: 20% and 15.3% compared with 8.8% and 7.2%. Distribution of other serogroups was similar for both series. Therefore the most striking differences were the greater number of autoagglutinating organisms in asymptomatic UTI and of O6 and O75 serogroups in symptomatic UTI.
    Digital Access Access Options