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- ArticleDavis KL, Mohs RC, Tinklenberg JR, Pfefferbaum A, Hollister LE, Kopell BS.Science. 1978 Jul 21;201(4352):272-4.Nineteen normal male subjects received 1.0 milligram of physostigmine or 1.0 milligram of saline by a slow intravenous infusion on two nonconsecutive days. Physostigmine significantly enhanced storage of information into long-term memory. Retrieval of information from long-term memory was also improved. Short-term memory processes were not significantly altered by physostigmine.