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  • Book
    edited by Robert T. Means Jr.
    Summary: This major new comprehensive guide focuses on particular topics in the field of nutritional anemias, with in-depth coverage on each relevant nutrient whose deficiency can cause anemia, their metabolism, dietary requirements and related information. This book presents the unique hematological, and non-hematological, manifestations of each deficiency, the varied settings and causes of deficiency, interactions with other problems, diagnostic approaches and tools, synthesizing the perspectives of epidemiology, public health, and clinical hematology. Covering approaches to medical management in individuals, as well as in susceptible populations such as children, pregnant women and the elderly; and preventive strategies, such as supplementation and fortification, this exceptional text will appeal to a wide audience, from the clinician learning about the epidemiology and public health aspects of food fortification, to the public health practitioner who needs to understand clinical approaches to key nutritional anemia issues.

    Contents:
    General hematology of anemia / Robert Means
    Impact of anemia : overview / Robert Means
    Fortification of food : principles and practice / Richard Hurrell and Ines Egli
    Nutritional anemia and its non-nutritional influences in the developing world / Julia Shaw, Jennifer Gutierrez, and Jennifer Freidman
    Laboratory assessment of iron status / Carlo Brugnara
    Iron deficiency without anemia / Gordon McLaren and Barry Skikkne
    Treatment of iron deficiency in adults / Robert Means
    Dietary iron deficiency anemia in children / Clara Lo and Michael Jeng
    Physiology of copper balance and metabolism / Robert Means
    Clinical syndromes of copper deficiency / Darryl Williams
    Vitamin D / Ellen M. Smith and Vin Tangpricha
    Nutritional anemia during pregnancy / Robert Means
    Vegetarianism and other restricted diets / Asok C. Antony
    Nutritional syndromes with anemia : alcohol / Sylvia Bottomley
    Anemia following bariatric surgery / Benjamin Person and Raul Rosenthal.
    Digital Access Cambridge 2019
  • Article
    Chaubey RC, Kavi BR, Chauhan PS, Sundaram K.
    Mutat Res. 1978 May;57(2):187-91.
    Male Swiss mice were assigned to 6 groups of either 3 or 4 animals each. 3 groups were given hycanthone methanesulfonate intraperitoneally, at 40, 80 or 120 mg/kg, respectively; the dose was repeated after an interval of about 24 h. At the same time 2 groups received maleic hydrazide at 100 or 200 mg/kg, and the remaining group was given dimethyl sulfoxide which was used as a solvent for both drugs. 6 h after the second injection, the mice were killed and bonemarrow preparations were made. Hycanthone induced a significant increase in the frequency of micronuclei in the polychromatic erythrocytes and suppressed the P/N ratio significantly. However, there was no dose-response relationship. Maleic hydrazide, on the other hand, failed to influence the incidence of micronuclei or the ratio of poly- to normo-chromatic erythrocytes.
    Digital Access Access Options