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  • Book
    by Paul M. Selzer, Richard J. Marhöfer, Oliver Koch.
    Summary: This book introduces readers to the basic principles of bioinformatics and the practical application and utilization of computational tools, without assuming any prior background in programming or informatics. It provides a coherent overview of the complex field and focuses on the implementation of online tools, genome databases and software that can benefit scientists and students in the life sciences. Training tutorials with practical bioinformatics exercises and solutions facilitate the understanding and application of such tools and interpretation of results. In addition, a glossary explains terminology that is widely used in the field. This straightforward introduction to applied bioinformatics offers an essential resource for students, as well as scientists seeking to understand the basis of sequencing analysis, functional genomics and protein structure predictions.

    Contents:
    The Biological Foundations of Bioinformatics
    Biological databases
    Sequence Comparisons and Sequence-Based Database Searches
    The decoding of eukaryotic genomes
    Protein Structures and Structure-Based Rational Drug Design
    The Functional Analysis of Genomes
    Comparative genome analyses.
    Digital Access Springer 2018
  • Article
    Budtz-Jörgensen E.
    J Clin Periodontol. 1977 Dec;4(5):117-28.
    Denture stomatitis (chronic atrophic candidosis) is a very common complication to the wearing of complete dentures. The infection is due to a contamination of the denture by yeasts. In a number of studies the clinical effect of Hibitane when used as a denture disinfectant has been studied. It was found that Hibitane (0.2--2%) caused a significant amelioration of inflamed palatal tissues and a reduction in the number of yeast cells harbored on the palatal mucosa and the fitting surface of the dentures. However, relapse of the infection was frequent after treatment was sustained. It was concluded that Hibitane could not be recommended for routine denture disinfection, first, because it caused staining of the dentures, second, because of the relative resistance of the yeast to the action of the drug. However, it seems justified to use Hibitane prophylactically as a denture disinfectant in patients who are highly susceptible to developing disseminating or systemic candidosis. Hibitane is a valuable drug in the treatment of denture stomatitis when used as a denture disinfectant.
    Digital Access Access Options