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- BookNick Roland, MBChB, MD, FRCS (ORL), Consultant ENT/Head and Neck Surgeon, ... Show More University Hospital Aintree, Liverpool, UK; Southport and Ormskirk NHS Trust, Lancashire, UK, Duncan McRae, MD, FRCS (ORL), Consultant ENT Surgeon, Colchester General Hospital, Colchester, UIK, Andrew W. McCombe, MD, FRCS (ORL), Consultant ENT Surgeon, City Hospital, Dubai Healthcare City; Adjunct Clinical Professor of Surgery, Mohammed Bin Rashid University Medical School, Dubai, UAE.
- ArticleTaylor DE, Shermier M, Grant RB.Can J Microbiol. 1978 May;24(5):600-7.Chloramphenicol resistance in salmonella obtained from clinical sources in Ontario was previously found to be often mediated by R plasmids of the H2 incompatibility group. In the present study 40 salmonella strains resistant to one or more of kanamycin, streptomycin, sulfonamides, or tetracycline but sensitive to chloramphenicol, were investigated to determine if they contained R plasmids. Self-transmissible plasmids were isolated from 17 of the strains, and 7 of those showed the bacteriophage inhibition and thermosensitive mechanism of transfer characteristic of H2 plasmids. Entry exclusion and incompatibility experiments confiremd their classification. The results demonstrate that in this population of salmonella, R plasmids of the H2 group are prevalent. Experiments with plasmid-specific phages indicate that the plasmids of this sample, which are not in the H2 group, do not belong to any of the F, I, N, P, or W incompatibility groups.