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  • Book
    Maryanne Tate Maltby.
    Summary: "A Dictionary of Hearing is a comprehensive reference that defines terms used in audiology, ENT, and related areas. This dictionary covers a wide range of terms in audiology and will be very useful to students and professionals in the field of hearing, including audiologists, nurses and doctors, teachers of the deaf, and speech and language therapists. Key features: Contains more than 4,000 common and uncommon audiological terms with clear meanings; Includes the etymology of words, providing a historical context for students; Entries have the breadth and depth of definition that students and professionals need. This dictionary is an essential resource that all professionals in the field of audiology will want to have at their fingertips"-- Provided by publisher.
    Digital Access
    Provider
    Version
    Thieme MedOne ComSci
    [2014]
    Thieme MedOne Otolaryngology
    2014
  • Article
    Maloney MA, Dorie MJ, Lamela RA, Rogers ZR, Patt HM.
    J Exp Med. 1978 Apr 01;147(4):1189-97.
    The kinetics of bone marrow replacement was studied in W/WV mice implanted with gbj/bgj (beige) stem cells, with the characteristic beige neutrophil marker as a criterion of the takeover of host marrow by donor marrow. A hyperbolic pattern of W/WV marrow replacement conforming to a log dose-response was observed in experiments encompassing a 50-fold range of bgj/bgj inoculum doses and a 2-yr period of observation. The dose-response relationships were consistent with random seeding of stem cells in the host marrow coupled with a decreasing efficiency of secondary colonization by local migration. Application of single-hit Poisson sampling statistics to the dose-response data led to the hypothesis that mouse bone marrow is compartmentalized into essentially self-contained stem cell regulatory volumes or domains. We estimate that W/WV marrow contains about 2,600 stem cells regulatory units with an average volume of about 10(8) micron3, a dimension consistent with the presumptive role of short-range cell-cell interactions in the regulation of pluripotent stem cells. Our analysis of the dose-response data is also indicative of the discontinuous and limited nature of local stem cell migration in a cellular marrow, a consideration that may be of practical as well as theoretical interest.
    Digital Access Access Options