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- BookKeith L. Moore, T.V.N. (Vid) Persaud, Mark G. Torchia.Summary: "Covering the essentials of normal and abnormal human development for students in a variety of health science disciplines, Before We Are Born: Essentials of Embryology and Birth Defects, 10th Edition, reflects new research findings and current clinical practice through concise text and abundant illustrations. This edition has been fully updated by the world's foremost embryologists and is based on the popular text, The Developing Human, written by the same author team. It provides an easily accessible understanding of all of the latest advances in embryology, including normal and abnormal embryogenesis, causes of birth defects, and the role of genes in human development."--Provided by publisher.
Contents:
Introduction to human development
Human reproduction
First week of development
Second week of development
Third week of development
Fourth to eighth weeks of human development-- Fetal period : the ninth week to birth
Placenta and fetal membranes
Body cavities, mesenteries, and diaphragm
Pharyngeal apparatus, face, and neck
Respiratory system
Alimentary system
Urogenital system
Cardiovascular system
Musculoskeletal system
Nervous system
Development of eyes and ears
Integumentary system
Human birth defects
The cellular and molecular basis of development.Digital Access ClinicalKey 2020 - ArticleIngolia TD, Koshland DE.J Biol Chem. 1978 Jun 10;253(11):3821-9.Small phospholipid vesicles (liposomes) fuse upon calcium addition as demonstrated by electron microscopy, light absorbance increases, and mixing of original liposome contents within the boundaries of the fused liposome. The integrity of the fusion event is demonstrated by a novel assay based on the luminescence of firefly extract when mixed with ATP. Subsequent addition of valinomycin or the calcium ionophore A23187 leads to further fusion as shown by electron microscopy, light microscopy, and additional absorbance increase. Concomitant with this second absorbance increase is an increase in the amount of calcium that associates with the liposomes. This increased calcium association is more than can be accounted for by equilibration of 5 mM Ca2+ across the membrane and must indicate exposure of extra calcium binding sites. Binding of calcium to the inner side of the membrane may catalyze the second stage of liposome fusion.