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  • Book
    edited by L.A.A. Ooms and A.D. Degryse, A.S.J.P.A.M. van Miert.
    Summary: The success of a scientific workshop depends on a delicate blend of many types of ingredients. Most important is to select a provocative topic which is at the forefront of a current investigative study. Coupled together with a relatively small but distinguished group of active research scientists known for their continued record of contributing significant findings, one has the firm foundation for an exciting and rewarding investment of time and effort. This was the setting for the first workshop organized by the European Association for Veterinary Pharmacology and Toxicology. Ruminants have been domesticated for many centuries and have served mankind as a source of dairy products, meat, wool and power. The ruminant stomach has long been - and still is - a major concern for physiologists, pathologists, clinicians and pharmacologists. This workshop was organized and convened in an attempt to strengthen the basic science of the ruminant stomach, as it applies to an economically important group of mammals. To achieve this, various topics were covered by specialists which ensured presentation of new data, followed by discussions. In this book, reviews are presented on the different topics: motility (control and regulation, neurotransmitters and endogenous substances involved); flow of digesta (comparative aspects, role of content and metabolites); food intake; rumen metabolism (chemical manipulation, metabolism of xenobiotics and drugs); pharmacology of forestomach motility and, the reticulo-rumen as a pharmacokinetic compartment.

    Contents:
    1. The control of the motility of the reticulo-rumen
    2. Reticulo-rumen and gastroduodenal junction motility
    3. Neurotransmitters/neuromodulators involved in the motor and secretory functions of the ruminant stomach: a Histochemical, radioimmunological, immunocytochemical and functional approach
    4. Reticulo-rumen motility: in vitro and in vivo effects of endogenous substances
    5. Forestomach: control of digesta flow
    6. Comparative studies of food propulsion in ruminants
    7. Metabolic and endocrine controls of food intake in ruminants
    8. Rumen microbial metabolism of plant secondary compounds, xenobiotics and drugs
    9. Chemical manipulation of rumen metabolism
    10. The rumen as a pharmacokinetic compartment
    11. Drug-induced effects on reticular groove reflex, eructation and rumination
    Index of subjects.
    Digital Access Springer 1987
  • Article
    Iden DL, Rogers RS, Schroeter AL.
    Arch Dermatol. 1978 Apr;114(4):564-6.
    A patient with papulonecrotic tuberculid had a pruritic papular eruption associated with constitutional symptoms. The eruption flared whenever the patient received low doses of prednisone to control symptoms of temporal arteritis. A cervical lymph node biopsy specimen demonstrated acid-fast bacilli, and Mycobacterium bovis grew on the cultures. The eruption cleared completely with antituberculous therapy. This case demonstrated the clinicopathologic findings compatible with a diagnosis of papulonecrotic tuberculid. Skepticism regarding the existence of papulonecrotic tuberculid is probably a result of the current decreased prevalence of untreated tuberculosis, and the subsequently increased rarity of this entity.
    Digital Access Access Options