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- Book[edited by] Karen Whalen, PharmD, BCPS, FAPhA (Clinical Professor, ... Show More Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, Florida) ; collaborating editors, Carinda Feild, PharmD, FCCM (Clinical Associate Professor, Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, St. Petersburg, Florida), Rajan Radhakrishnan, Pharm, MSc, PhD (Professor of Pharmacology, College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates).Summary: "Lippincott Illustrated Reviews: Pharmacology, Seventh Edition, is the updated, enhanced version of the student-favorite resource for essentials of medical pharmacology. The first-and-best resource, the Lippincott Illustrated Reviews series features clear, effective writing and hundreds of illustrations for ideal rapid review and the assimilation of complex information. Clear, sequential images present mechanisms of action and focus on showing rather than telling students how drugs work. Nearly 600 annotated, full-color illustrations visually explain complex processes! Outline format ideal for concise review and foundational learning"-- Provided by publisher.
Contents:
I: Principles of drug therapy
II: Drugs affecting the autonomic nervous system
III: Drugs affecting the central nervous system
IV: Drug affecting the cardiovascular system
V: Drugs affecting the endocrine system
VI: Chemotherapeutic drugs
VII: Special topics in pharmacologyDigital Access LWW Health Library (Medical Education) 2019 - ArticleTuresson I.Acta Med Scand. 1978;203(4):247-55.Cell suspensions of bone marrow and lymphoid tissue from 85 patients with monoclonal gammapathy were investigated by a direct immunofluorescence procedure for the detection of intracellular immunoglobulin alpha, mu, gamma, kappa and lambda chains. Serum Ig levels were determined and daily syntheric rates estimated. In all cases the majority of Ig-containing bone marrow cells contained the same Ig class as that of the M-component in serum or urine indicating a diffuse distriubtion of these clones in the bone marrow. This was observed not only in myeloma but also in benign monoclonal gammapathy (BMG) and lymphoma with an M-component. The M-component producing clone could be traced to extramedullary lymphoid tissue in myeloma but usually not in BMG. A positive correlation was found between the calculated synthetic rate of the M-component and the number of Ig-containing cells in the bone marrow and some indication was found that the synthetic rate per cell might be lower in IgM and IgG than in IgA monoclonal gammapathy. The depressed level of polyclonal Ig in myeloma and to some extent in BMG was parallelled by a diminished number of Ig-containing cells in the bone marrow.