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- ArticleHinnen A, Hicks JB, Fink GR.Proc Natl Acad Sci U S A. 1978 Apr;75(4):1929-33.A stable leu2- yeast strain has been transformed to LEU2+ by using a chimeric ColE1 plasmid carrying the yeast leu2 gene. We have used recently developed hybridization and restriction endonuclease mapping techniques to demonstrate directly the presence of the transforming DNA in the yeast genome and also to determine the arrangement of the sequences that were introduced. These studies show that ColE1 DNA together with the yeast sequences can integrate into the yeast chromosomes. This integration may be additive or substitutive. The bacterial plasmid sequences, once integrated, behave as a simple Mendelian element. In addition, we have determined the genetic linkage relationships for each newly introduced LEU2+ allele with the original leu2- allele. These studies show that the transforming squences integrate not only in the leu2 region but also in several other chromosomal locations.
- BookFrank Honigsbaum.Summary: The author uses extensive records to describe the process by which the NHS was created. An historian, with an intimate knowledge of current NHS problems, he provides a valuable resource for all those interested in this area. This book should be of interest to students of history, politics, social policy, public administration. Nielsen 9780415017398 20160527
Contents:
Part One: Prelude to Planning 1. Failure of Reform 2. Ministry Rejects Takeover of Voluntary Hospitals 3. Pressure for Hospital Organization
Part 2: GP Service 4. Salaried Service Under Municipal Control 5. Doctors Reject Municipal Control 6. Ministry Resistance to Compromise 7. Doctors Reject White Paper 8. Retreat to Panel System 9. Bevan's Pragmatic Compromise Part Three: Moran's Consultant Service 10. Moran Organizes Consultants 11. Who Is a Consultant? Who Should Decide? 12. Struggle for Regional Control 13. Bevan's Concessions - More to Consultants or GPs? Part Four: National Hospital Service 14. No Charge for Hospital Care 15. Deadlock in Negotiations 16. Hospitals are Nationalized Part Five: Free and Complete Care for All 17.Financial Constraints 18. Beveridge Pressure 19. NHS Costs 20. Medical Movement Toward Universal Coverage Part Six: Assessment 21. Civil Servants and Doctors: Their Influence Compared Appendix: The Crisis in NHS Negotiations, April 1948, Notes and References, Bibliography, Index. Nielsen 9780415017398 20160527Print 1989 - BookVal Hopwood, Clare Donnellan.Contents:
History and background of traditional Chinese medicine in neurological conditions
Researching a complex intervention
Current context : neurological rehabilitation and neurological physiotherapy
Western medical acupuncture in neurological conditions
Practical application of western medical acupuncture in neurological conditions
Acquired brain injury : stroke, cerebral palsy, and traumatic brain injury
Parkinson's disease and related conditions
Multiple sclerosis
Spinal cord injury and disease
Peripheral nervous system disorders
Motor neurone disease
Pulling it together.Digital Access ScienceDirect 2010