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  • Book
    Huawei Li, Renjie Chai, editors.
    Summary: This book systematically discusses the pathogenesis, prevention, and the current and potential clinical treatment of hearing loss, as well as the latest advances in hearing research. Hearing loss is a prevalent sensory disorder, which according to a 2015 World Health Organization (WHO) report affected 9% of the global population in 2015. As populations continue to age, more and more people are suffering from the condition, with 60% of those aged between 65 and 75 affected. Hearing loss seriously affects patients' ability to work ability and quality of life, and as such deafness has become an increasingly urgent social problem around the globe. Sensorineural hearing loss is mainly caused by damage to the hair cells (HCs), and the subsequent loss of spiral ganglion neurons (SGNs). Damage to the HCs in the inner ear can result from exposure to loud noises and environmental and chemical toxins as well as genetic disorders, aging, and certain medications. This book provides ENT specialists and researchers, as well as individuals affected a comprehensive introduction to the field of hearing loss.

    Contents:
    Hair cell regeneration
    Hair cell Protection against ototoxic drugs induced hearing loss
    Noise Induced Cochlear Synaptopathy and Ribbon Synapse Regeneration: repair process and therapeutic target
    Protection and prevention of age-related hearing loss
    Diagnosis, Intervention and Prevention of Genetic Hearing Loss
    Protection of spiral ganglion neurons and prevention of auditory neuropathy
    Advances in Diagnosis and Treatment of Tinnitus
    Cochlear implantation and rehabilitation
    Non-implantable artificial hearing technology
    Stem cells: a new hope for hearing loss therapy.
    Digital Access Springer 2019
  • Book
    by Jan Merrill-Oldham and Paul Parisi.
    Summary: The growing interest in preservation of library collections has fueled the use of the "Library Binding Institute Standard for Library Binding". Because the "LBI Standard" is based on the assumption that the reader understands the machinery and processes employed by the library binding industry, descriptive text is minimal. This guide translates the technical language of the "LBI Standard" into usable information that should enable librarians to use the "LBI Standard" to its fullest advantage. The book is both a supplement and complement to the "LBI Standard". The numbering scheme parallels the "LBI Standard" to facilitate the side-by-side reading of the two documents and offers preservation information in concise format. Since the purpose of the guide is to clarify its parent document and to improve communication between librarians and binders, use of terminology has been strictly limited, so that terms correspond to those found in the "LBI Standard" and no analogous terms are substituted. The illustrations are used to enhance the text, in order to help readers better understand what they are seeing as they study the features of a bound volume. Appendices are also included as a series of management and training tools. Nielsen 9780838933916 20160527
    Print c1990
  • Article
    Lee YH, Blakesley RW, Smith LA, Chirikjian JG.
    Nucleic Acids Res. 1978 Mar;5(3):679-89.
    Type II restriction endonucleases Bam HI and Eco RI were covalently coupled to Sepharose. These insolubilized enzymes generated fragment patterns for several viral DNAs identical to those produced by the respective free enzymes. Conditions for optimal activity were similar for both bound and unbound forms of the enzymes. Insolubilization improved thermal stability of Bam HI and Eco RI. The bound enzyme can be recovered from reaction mixtures and reused several times. Upon storage at 4 degrees C, coupled endonucleases remained stable for several months.
    Digital Access Access Options