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• Book

  Clinical handbook of psychiatry & the law. Fifth edition.

  Thomas G. Gutheil, Paul S. Appelbaum.

  Contents:
  Confidentiality and privilege
  Legal issues in emergency psychiatry and involuntary commitment
  Legal issues in inpatient psychiatry
  Malpractice and other forms of liability
  Competence and substitute decision-making
  Forensic evaluations
  Clinicians and lawyers
  The clinician in court.

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  Ovid

  2020

  LWW Health Library

  2020
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• Article

  Acute hematogenous pyelonephritis in the rabbit. Electron microscopic study of Escherichia coli localization and early acute inflammation.

  Johnston WH, Latta H.

  Lab Invest. 1978 Apr;38(4):439-46.

  Injection of approximately 10(6) to 10(9) Escherichia coli into the renal arteries of rabbits resulted in retention of sufficient numbers of organisms in renal vessels to permit study of the mechanism of localization by electron microscopy. After injection of the bacterial suspension, perfusion fixation was used to maintain open vascular contours. Individual organisms were found to adhere to the endothelium of glomerular and intertubular capillaries, and ruthenium red staining demonstrated a close interaction between the largely polysaccharide bacterial microcapsule and the sialoglycoprotein endothelial surface coat. Thus, individual E. coli seem to localize in the rabbit kidney in this model by sticking to the endothelial surfact coat of the renal vessels. After localization, polymorphonuclear leukocytes and monocytes appeared in the capillaries and phagocytosed the bacteria. Phagocytosis of bacteria was evident at 10 minutes and was almost complete at 60 minutes and, although less frequent, were associated with small amounts of fibrin at 60 minutes. This acute inflammation and thrombosis may be mediated by activation of complement through the alternate pathway.

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  PubMed