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  • Book
    Edmund Liem, editor.
    Summary: This book is designed to enable (pediatric) dentists to recognize the signs and symptoms of sleep disorders in their pediatric patients, it will help to understand the potential negative impact of a sleep disorder on the metabolic and cognitive neurodevelopment of a child and how to collaborate with others to implement appropriate management, including early (dentofacial) orthopedic intervention when necessary. A detailed examination of craniofacial signs and behavioral symptoms should alert the dentist to the potential presence of (a) sleep disorder(s) in children. The various treatment options other than positive airway pressure (PAP) therapy or adeno-tonsillectomy, which should be considered as potential life-saving short-term solutions, are discussed and shown. Treatment options that are discussed are dentofacial orthopedics (including orthotropics), orthodontics and orofacial myology; sample case outcomes are shown to demonstrate achievable results. Sleep Disorders in Pediatric Dentistry will serve as an excellent clinical guide that takes full account of recent developments in the field and explains the enormous potential that dentist can attribute to the patients overall (future) health. This book is also an excellent introduction for the general dentist to the medical world of (pediatric) sleep disorders. In this book a team of co-authors (2 medical doctors; 3 dental specialists; 3 general dentists and 3 dental hygienists) shared their knowledge that will educate the (pediatric) dentists about Sleep Disorders in Pediatric Dentistry.
    Digital Access Springer 2019
  • Article
    Kipshidze NN, Korotkov AA, Chapidze GE, Marsagishvili LA, Todua EI.
    Kardiologiia. 1978 Mar;18(3):18-28.
    The effect of the nucleoside Inosie-F (inosin) on the intracardiac hemodynamics and the contraction and relaxation of a diseased myocardium was studied in the clinic and in experiments. An examination was made of 102 patients with macrofocal myocardial infarction (22 received inosin by intravenous drip in a single dose of 200 mg in the acute stage of infarction; 60 patients were given inosin pills in a daily dose of 800 mg in the restoration period for one month, and 20 patients were given placebo). Comparative appraisal of treatment in the period of rehabilitation showed prevailing improvement in the condition of individuals treated with inosin, positive ECG dynamics, increase of cardiac output and decrease of peripheral resistance. In experiments on 28 dogs with a model of acute myocardial ischemia a noticeable improvement in myocardial contraction and relaxation in the absence of negative ECG dynamics was recorded after intravenous infusion of inosin. Inosin achieves maximum effect by 60-90 mins after the beginning of infusion.
    Digital Access Access Options