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  • Book
    Monica M. Taylor.
    Summary: This innovative resource offers a unique, multidisciplinary approach for the utilization of planning theory to eliminate health disparities in rural communities. The book provides tools in the public health, policy, and planning disciplines to help resolve significant differences in life expectancy and quality of life in these communities, concluding with a progressive vision for alleviating geographical health disparities on a local, national, and global scale. Chapters highlight models and approaches best suited to addressing this public health concern, suggesting action strategies focused around each of the three focus areas: 1. Public health: Elucidation of the contextual factors impacting the health of rural communities by: reporting statistical updates on a range of chronic and infectious diseases that disproportionately affect rural populations both globally and in the U.S.; providing discourse on the importance of addressing critical social determinants (global and national) that impede optimal health outcomes among rural populations; and, acknowledging the compositional factors of individuals who reside in rural spaces. 2. Public policy: Application of specific policy models to garner both public and political will towards sustainable policy change to improve healthy living in rural spaces. 3. Rural planning: Identification of national and international planning models that can be used to design strategic plans targeted to improve quality of life, create sustainable development, and establish economic well-being and growth in rural communities. Rural Health Disparities: Public Health, Policy, and Planning Approaches will find an engaged audience among non-profit organizations, planners, public health practitioners, policy analysts, and public interest groups, as well as rural health advocates and students enrolled in planning, public policy, and/or public health courses.
    Digital Access Springer 2019
  • Article
    Nichols JC, Baseman JB.
    Infect Immun. 1978 Mar;19(3):854-60.
    Ribosomal ribonucleic acid (rRNA) synthesis by virulent Treponema pallidum was monitored by incorporation of [(3)H]uridine into trichloroacetic acid-precipitable counts and examination of radiolabeled rRNA on polyacrylamide gels. Verification that rRNA synthesis originated with T. pallidum was based upon co-electrophoresis with Escherichia coli rRNA, proportionate reductions in the amount of rRNA synthesized when numbers of treponemes were decreased, and inclusion of appropriate animal cell controls. The rate of treponemal rRNA synthesis was greater at temperatures of 37 and 39 degrees C than at 33 degrees C; rRNA synthesis was inhibited at 4 and 42 degrees C and was effectively inhibited by actinomycin D. Kinetic experiments indicated that the majority of rRNA synthesis occurred early after extraction of treponemes from infected rabbit testicular tissue. Polyacrylamide gel profiles demonstrated the capacity of virulent T. pallidum to synthesize and process RNA to 23s, 16s, and 4 to 5s classes. Although motility of T. pallidum appeared unaffected during longer periods of incubation, pulselabeling experiments confirmed significant reductions in the rate of rRNA synthesis. When the effect of various environmental conditions upon rRNA synthesis was investigated, optimal synthesis was found to occur in an atmosphere of 20% oxygen whereas virtually no synthesis was observed under anaerobic or low-oxygen conditions.
    Digital Access Access Options