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  • Book
    editors-in-chief, Charles D. Bluestone, MD, FACS, FAAP, ... Show More Distinguished Professor of Otolaryngology, University of Pittsburgh School of Medicine, Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvannia ; Jeffrey P. Simons, MD, FACS, FAAP, Associate Professor of Otolaryngology, University of Pittsburgh School of Medicine, Divisiono of Pediatric Otolaryngology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvannia ; Gerald B. Healy, MD, FACS, FRCS (Eng), FRCS (Irs), Professor of Otology & Laryngology, Harvard Medical School, Emeritus Healy chair in Otolarynoglogy, Boston Children's Hospital, Emeritus Surgeon-in-Chief, Boston Children's Hospital, Boston, Massachusetts, Past President, American College of Surgeons.
    Contents:
    Section 1 Basic science/general pediatric otolaryngology
    Section 2 Ear and related structures
    Section 3 The Nose, paranasal sinuses, face, and orbit
    Section 4 The Mouth, pharynx, and esophagus
    Section 5 The Airway
    Section 6 The Head and neck
    Section 7 Communication disorders.
    Digital Access R2Library v.1-2 , 2014
    Limited to 1 simultaneous user
  • Article
    Mukada T, Sasano N, Sato E.
    Cancer. 1978 Apr;41(4):1399-404.
    In order to grade objectively and characterize dysplastic and precancerous esophageal epithelium its DNA content was measured by cytofluormetric methods and compared to normal and cancerous esophageal epithelium. This yielded the following results. With transition of the esophageal eipthelium from mild dysplasia to severe dysplasia and finally to in situ carcinoma, Feulgen-DNA values showed patterns characteristic of a tetraploid population. They lacked prominent peaks which were usually observed with invasive carcinomas. Dominant near-tetraploid population and definite tetraploid-octoploid populations were characteristic of severe dysplasia or carcinoma. The mean Feulgen-DNA values were significantly larger in severe dysplasia than in the lesser grade of dysplasia as well as the normal epithelium. However, this was not the rule in the full blown carcinomas. It would appear that the esophageal cytophotometric patterns are analogous to those previously observed in the skin and uterine cervix.
    Digital Access Access Options