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  • Book
    Zhao Wang, editor.
    Summary: "This book provides an overview of recent advances in the study of aging and aging related diseases, discussing the topics at individual, organ, tissue, cell, and molecular levels. It also presents studies on the biomarkers of aging and anti-aging interventions. Aging has been becoming a global health problem. However it was not possible to determine aging as we usually diagnose a disease because there are few biomarkers for age estimation. Since ancient times, people have been seeking anti-aging substances and methods for achieving immortality, while the scientific study of aging has only existed for 100 years. This book appeals to researchers both in institutes and in pharmaceutical companies interested in further studies in this field"--Publisher's description.

    Contents:
    Systems biology in aging research / Xian Xia, Jing-Dong J. Han
    Circular RNA in aging and age-related diseases / Deying Yang, Katie Yang, Mingyao Yang
    Noncoding RNAs in cardiovascular aging / Yongqin Li, Yujiao Zhu, Guoping Li, Junjie Xiao
    Epigenetic regulation of vascular aging and age-related vascular diseases / Yang-Nan Ding, Xiaoqiang Tang, Hou-Zao Chen, De-Pei Liu
    Apoe and neurodegenerative diseases in aging / Yuemiao Yin, Zhao Wang
    Brain aging: HSP90 and neurodegenerative diseases / Kun Wang, Yu Shang, Fei Dou
    Aging of human adult stem cells / Han Xie, Shouliang Zhao, Shangfeng Liu
    Mechanisms of hematopoietic stem cell ageing and targets for hematopoietic tumour prevention / Min Liao, Jianwei Wang
    Microbiota and aging / Maoyang Lu, Zhao Wang
    Intestinal homeostasis and longevity: Drosophila gut feeling / Xiaolan Fan, Uma Gaur, Mingyao Yang
    Aging kidney and aging-related disease / Zhongchi Li, Zhao Wang
    Aging of the bone / Yu Wei, Yao Sun
    Ovarian aging and osteoporosis / Liyuan Li, Zhao Wang
    Biomarkers of aging / Xiaojuan Bai
    Pharmaceutical intervention of aging / Minxian Qian, Baohua Liu
    Application of stem cell technology in antiaging and aging-related diseases / Yanqiu Yu
    Which is the most reasonable anti-aging strategy: meta-analysis / Yaru Liang, Zhao Wang
    Digital Access Springer 2018
  • Article
    Marks SC.
    Am J Anat. 1978 Jan;151(1):131-7.
    Spleen cells from normal rats are known to cure osteopetrosis in ia littermates within 3 weeks. In this study cell suspensions from liver, thymus, bone marrow, salivary gland, skeletal muscle and brain from normal rats were tested for their ability to cure osteopetrosis in ia littermates whose ability to reject these cells had been suppressed by whole-body irradiation. Cells from liver, thymus and bone marrow cured the disease as effectively as spleen cells from normal littermates. Mutants that received cells from salivary gland, muscle and brain remained osteopetrotic. These data suggest that some cell found in spleen, liver, thymus and bone marrow of 10-day-old normal rats, such as a lymphoid cell or stem cell, can restore hemopoiesis and bone resorption in osteopetrotic (ia) rats.
    Digital Access Access Options