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  • Journal
    Digital Access
    Provider
    Version
    MDPI
    v. 1-, 2010-
    PubMed Central
    v. 7-, 2016-
  • Article
    Richard GA, Garin EH, Fennell RS, Walker RD.
    Adv Pediatr. 1977;24:339-98.
    Hypertension is a major medical problem with significant short- and long-term sequelae. Previous investigators have reported childhood hypertension to be secondary and when sexondary, renal. However, recent studies have shown primary (essential) hypertension to be more prevalent than secondary. Children with blood pressures at the 95th percentile for age deserve comprehensive evaluation and follow-up. Those with systemic evidence of side-effects will require therapy. Modern therapy should be based on pathophysiologic principles which include an understanding of volume-dependent and renin-dependent hypertension. The stepwise approach to therapy will produce the maximal therapeutic benefit.
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