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- ArticleRadoutcheva T, Popov C, Veljanov D, Bondarenko VM.Zentralbl Bakteriol Orig A. 1977 Nov;239(3):352-60.The oxygen uptake and dehydrogenase activity of avirulent xyl+ and xyl- str hybrids (KCP-), obtained from virulent strains Sh. flexneri (Sh. flexneri 222 5 a and Sh. flexneri M42-432a) and donor strain E. coli AB 313, devoid of ability for intracellular multiplication in epithelial cells are studied. Some tricarboxylic acid intermediates, hexoses and pentoses were used as substrates. A definite tendency has been established, indicating a decreased rate of oxygen consumption and dehydrogenase activity of the hybrids, compared to the respiratory activity of the virulent recipient strains tsh. flexneri in all substrates used.