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  • Book
    Massimo Tonolini, editor.
    Summary: Aimed at practicing clinicians and radiologists, this volume provides up-to-date, detailed information on potentially severe urinary tract infections (UTIs), which frequently require intensive in-patient antibiotic therapy, percutaneous or surgical treatment. UTIs are the most prevalent infectious illness, and account for hundreds of thousands of emergency and hospital admissions yearly. Furthermore, UTIs are the most common (almost 40%) type of hospital-acquired infections, with bladder catheterisation being the key risk factor. According to the European Association of Urology guidelines, complicated urinary tract infections (C-UTIs) are those associated with structural or functional genitourinary abnormalities or with conditions that impair the host's defence mechanisms, leading to an increased risk of acquiring infection or therapy failure. Besides offering current perspectives from urologists, nephrologists, and specialists in infectious diseases, the book presents the techniques and highlights the role of ultrasound and contrast-enhanced ultrasound, nuclear medicine, multidetector computed tomography (CT) and magnetic resonance imaging (MRI) in providing comprehensive investigations of upper and lower tract UTIs, and of systemic infections from unknown sources. Cross-sectional imaging is currently recommended to confirm UTI, to assess severity and look for underlying treatable structural or functional abnormalities, in order to provide a consistent basis for a correct therapeutic choice. Furthermore, dedicated chapters illustrate the current status of UTI imaging in children and the expanding role and possibilities of interventional radiology in the treatment of severe urinary tract infections.
    Digital Access Springer 2018
  • Article
    Dupont E.
    Proc Eur Dial Transplant Assoc. 1977;14:321-7.
    A test using whole blood for antibody-dependent cell-mediated cytotoxicity has been assessed in kidney patients. The antibody-coated target system comprised lymphocytes isolated from a normal donor sensitised with rabbit anti-human lymphocyte serum. Comparison of results obtained with whole blood and isolated lymphocytes from the same patients shows that the whole blood test amplifies the differences between normal subjects, dialysis and transplant patients. It probably combines the effects of depressed lymphocyte function and lymphopenia and thus represent a more physiological in vitro correlate for in vivo immune function.
    Digital Access Access Options