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- Bookedited by Mario Manto, Thierry A.G.M. Huisman.Summary: "The Cerebellum: Disorders and Treatment, Volume 155 updates readers on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice, and (2) Therapy (including insights into innovative drug and rehabilitative approaches). The book's innovative structure discusses cerebellar disorders in children and adults as a continuum, with its companion volume, The Cerebellum: From Embryology to Diagnostic Investigations detailing embryology, anatomy, function and diagnostic investigations and neuroimaging, including conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies"--Publisher's description.
Contents:
Section I. Disorders. Fetal cerebellar disorders
Chiari 1 deformity in children: etiopathogenesis and radiological diagnosis
Cerebellar injury in preterm infants
Cerebellar involvement in Autism and ADHD
Recessive ataxias
Non-progressive congenital ataxias
Non-syndromic cerebellar ataxias associated with disorders of DNA single-strand break repair
Metabolic ataxias
Mitochondrial ataxias
Spinocerebellar ataxias
X-linked ataxias
Spastic ataxias
Episodic ataxias
Sporadic adult onset ataxia
Epigenetic cerebellar diseases
Essential tremor and the cerebellum
The cerebellum and dystonia
Cerebellar mutism syndrome
Cerebellar tumors
Cerebellar stroke in adults and children
Immune-mediated ataxias
Toxic-induced cerebellar syndrome: from the fetal period to the elderly
Endocrine disorders and the cerebellum: from neurodevelopmental injury to late-onset ataxia
Section II. Therapy. Drug treatment
Neurotransplantation therapy
Noninvasive stimulation
The cerebellum from the fetus to the elderly: history, advances and future challengesDigital Access ScienceDirect 2018 - ArticleKanoh S, Nishio A, Kawasaki H.Biken J. 1977 Jun;20(2):69-75.The development of pyrogenic tolerance was studied in rabbits treated with varying doses of E. coli lipopolysaccharide (LPS). The following results were obtained. 1) Development of pyrogenic tolerance seemed to proceed in two steps: that is, the first in which tolerance appeared rapidly and the second in which tolerance proceeded more gradually or steadily in response to repeated injections of a constant dose. 2) Tolerance induced by the latter method was not absolute; the rabbits were still sensitive to increased doses of LPS. 3) Rabbits immunized with E. coli vaccine lost their pyrogenic sensitivity of parent LPS to some extent. 4) Following intracisternal injection of LPS into tolerant rabbit, pyrogenic response was not decreased but rather enhanced in comparison with control. 5) The contents of nor-epinephrine and serotonin in the brain did not differ between normal and tolerant rabbits. 6) The mechanisms of endotoxin tolerance remain to be further studied.