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- ArticleLeclerc H, Mizon F, Boniface B, Boniface M.Ann Microbiol (Paris). 1977 Aug-Sep;128(2):253-69.The goal of this work is to describe the evolution of bacteria resistant to antibiotics in an aquatic environment and to compare their importance at different stages: human flora, sewage, surface water. Coliforms, fecal coliforms and Aeromonas are selected at test bacteria. The incidence of this difussion and influencing factors are discussed.