Bookedited by Yasushi Kawaguchi, Yasuko Mori, Hiroshi Kimura.
Summary: This book introduces and reviews several topics for each human herpesvirus. One of the most important features of the book is that it covers aspects of both basic research and clinical medicine. Herpesviridae, a family of double-strand DNA viruses, has unique biological features by which these viruses establish latency after primary infection and reactivate in later life. Nine human herpesviruses are known so far, and each of them causes a variety of diseases in both primary infection and reactivation. Since the discovery of each human herpesvirus, an abundance of findings related to them has accumulated in basic research and clinical medicine. However, the vast majority of biological features is still masked in mystery. Furthermore, a strategy of treatment and prevention has not yet been established for most human herpesviruses. A wide range of readers will be interested in this volume with its treatment of problematic points and latest findings in the field.
Contents:
Preface
Part I. Alphaherpesviruses
Chapter 1.The Role of Herpes Simplex Virus Glycoproteins in Mediating Cell Entry
Chapter 2. Virus assembly and egress of HSV
Chapter 3. Us3 protein kinase encoded by HSV: the precise function and mechanism on viral life cycle
Chapter 4. Oncolytic virotherapy by HSV
Chapter 5. Neurological disorders by human alphaherpesviruses
Chapter 6. Antiviral drugs against alphaherpesvirus
Chapter 7. Vaccine development for VZV
Part II. Betaherpesviruses
Chapter 8. Glycoproteins of HHV-6A and HHV-6B
Chapter 9. Betaherpesvirus virion assembly and egress
Chapter 10. Chromosomal Integration by Human Herpesviruses 6A and 6B
Chapter 11. Structural aspects of betaherpesvirus-encoded proteins
Chapter 12. Betaherpesvirus complications and management during stem cell transplantation
Chapter 13. Vaccine development for Cytomegalovirus
Part III. Gammaherpesviruses
Chapter 14. KSHV genome replication and maintenance in latency
Chapter 15. Signal transduction pathways associated with Kaposi's sarcoma-associated herpesvirus-related tumors
Chapter 16. Pathological features of Kaposi's sarcoma-associated herpesvirus infection
Chapter 17. EBV-encoded latent genes
Chapter 18. Encyclopedia of EBV-encoded lytic genes: an update
Chapter 19. Animal models of human gammaherpesvirus infections
Chapter 20. Gastritis-infection-cancer sequence of Epstein Barr virus-associated gastric cancer
Chapter 21. EBV in T/NK-cell tumorigenesis
Chapter 22. Vaccine development for Epstein-Barr Virus.