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- ArticleFraser EW.Mycopathologia. 1977 Oct 28;61(3):179-82.Two main types of immunological reactions are tested in twelve species of Candida. The agglutination reaction produces agglutination varying from +/-, or trace, to ++++ or .100 per cent agglutination. This is due to cross-reactions among the Candida and cannot be completely removed by adsorption. The precipitin reactions seem to give the most specific results, and most of the cross-reaction bands are adsorption-removable.