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- Bookedited by Jean-Marc Cavaillon and Mervyn Singer.Contents:
Front Matter
Inflammation through the Ages: A Historical Perspective / Jean-Marc Cavaillon
Inducers and Sensors of Inflammation. Pathogen-associated Molecular Patterns / Jean-Marc Cavaillon
Damage-associated Molecular Patterns / Jean-Marc Cavaillon
Bacterial Toxins / Marina Bernard, Cesare Montecucco
Venoms / Catarina Teixeira, Vanessa Moreira, José María Gutiérrez
Hypoxia as an Inducer of Inflammation / Ariel Brandwein, Clifford S Deutschman
Vaccine Adjuvants / Dennis M Klinman, Hidekazu Shirota
Pattern Recognition Receptors / Lauren Whitehead, Gordon D Brown
Inflammatory Cells. Monocytes and Macrophages / Irina N Shalova, Shilpi Saha, Subhra K Biswas
Neutrophils / Salvatore Cuzzocrea
Mast Cells: Master Drivers of Immune Responses against Pathogens / WX Gladys Ang, Soman N Abraham
Dendritic Cells in Inflammatory Disease / Bart N Lambrecht, Martin Guilliams, Hamida Hammad
Roles for NK Cells and ILC1 in Inflammation and Infection / Christian AJ Vosshenrich, James P Di Santo
Group 2 and 3 Innate Lymphoid Cells: New Actors in Immunity and Inflammation / Nicolas Serafini, James P Di Santo
Th9 Cells: From the Bench to the Bedside and Back Again / Benjamin J Ulrich, Matthew M Hufford, Mark H Kaplan
Th17 Cells / Mélissa Noack, Pierre Miossec
Platelets / Jack Levin
Epithelial Cells / Jill M Hoffman, Charalabos Pothoulakis
Inflammation: The Role of Endothelial Cells / J Steven Alexander, D Neil Granger, Norman R Harris
Inflammatory Mediators. IL-1 Superfamily and Inflammasome / Charles A Dinarello
TNF Superfamily / Salvatore Cuzzocrea
Interleukin-17 A-E / Giovanni Monteleone, Irene Marafini, Edoardo Troncone
IL-6 Superfamily / Toshio Tanaka, Masashi Narazaki, Tadamistu Kishimoto
Type I and II Cytokine Superfamilies in Inflammatory Responses / William F Carson, Steven L Kunkel
Chemokines and Chemotaxis / Osamu Yoshie, Kouji Matsushima
Lipid Mediators in Inflammation / Shuh Narumiya, Takehiko Yokomizo, Junken Aoki
Free Radicals in Inflammation / Andrew Cumpstey, Martin Feelisch
Proteases / Celine Deraison, Chrystelle Bonnart, Nathalie Vergnolle
Psychiatric Disorders and Inflammation / Robert Dantzer
Complement System / Peter A Ward, Claudia Kemper
Heat Shock Proteins / Willem Eden, Femke Broere, Ruurd van der Zee
Inflammation and Host Response. Inflammation and Coagulation / Marcel Levi
Fever: Mediators and Mechanisms / Joachim Roth
Pain / Christoph Stein
Inflammation, Hormones, and Metabolism / Muska Khpal, Mervyn Singer
Microenvironmental Regulation of Innate Immune Cell Function / Emily R Watts, Eilise Ryan, Sarah R Walmsley, Moira KB Whyte
Epigenetics of Inflammation / Vidula Vachharajani, Charles E McCall
Inflammation and Diseases. Allergy and Inflammation / Milena Sokołowska, Anna Głobińska, Cezmi A Akdis
Sepsis / Manu Shankar-Hari, Mervyn Singer
Autoimmunity and Inflammation / Shrikant Ramesh Mulay, Onkar P Kulkarni, Khader Rupanagudi, Hans-Joachim Anders
Psoriasis and Other Skin Inflammatory Diseases / Jaehwan Kim, James G Krueger
Rheumatoid Arthritis and Other Inflammatory Articular Diseases / Rogier M Thurlings, Sander W Tas, Paul Peter Tak*
Missing Heritability of Crohn's Disease and Implications for Therapeutic Targeting and Improved Care / Matthias Chamaillard
Inflammation and Transplantation / William M Baldwin,, Robert L Fairchild
Inflammatory Mechanisms in Chronic Obstructive Pulmonary Disease / Peter J Barnes
Obesity: A Complex Disease with Immune Components / Yuejun Liu, Karine Clément
Inflammation and Type 2 Diabetes / Marleen MJ Greevenbroek, Casper G Schalkwijk, Coen DA Stehouwer
Inflammation-Mediated Neurodegeneration: Models, Mechanisms, and Therapeutic Interventions for Neurodegenerative Diseases / Hui-Ming Gao, Yun Gao, Dezhen Tu, Yue Liu, Hui Zhou, Jau-Shyong Hong
Inflammation in Atherosclerosis / Mario AR Lauterbach, Larisa I Labzin, Eicke Latz
Acute Kidney Injury / Johan Mårtensson, Rinaldo Bellomo
Ischemia-Reperfusion Syndrome / Christophe Adrie, Sally A Shin, Mehran Monchi
Single-Nucleotide Polymorphisms and Inflammation / Evangelos J Giamarellos-Bourboulis
Resolution of Inflammation and Tissue Repair. Pentraxins in the Orchestration of Defense and Tissue Repair during the Acute Phase Response / Alberto Mantovani, Cecilia Garlanda, Barbara Bottazzi
Anti-Inflammatory Cytokines, Soluble Receptors, and Natural Antagonists / Willem Joost Wiersinga, Tom Poll
Regulatory T Cells / Luciana Berod, Katharina Lahl, Matthias Lochner, Christian T Mayer, Tim Sparwasser
Leukocyte Reprogramming / Jean-Marc Cavaillon
Roles of Specialized Proresolving Lipid Mediators in Inflammation Resolution and Tissue Repair / Matthew Spite, Charles N Serhan
Glucocorticoids / Heming Nicholas, Annane Djillali
The Neuroimmune Communicatome in Inflammation / Peder S Olofsson, Christine N Metz, Valentin A Pavlov
The Inflammatory Response in Tissue Repair / Nikolaos G Frangogiannis
Detection and Treatments. Biomarkers in Inflammation / Andreas Kortgen, Michael Bauer
In Vivo Imaging of Inflammation / Anne Roivainen, Antti Saraste
Novel Targets for Drug Development / Alan S Cross, Steven M Opal
Inflammation and Microbiota and Gut Reconditioning / Stig Bengmark
Natural Products as Source of Anti-Inflammatory Drugs / Shivaprasad H Venkatesha, Bodhraj Acharya, Kamal D Moudgil.Digital Access Wiley 2018 - ArticleHopper JE, Bostian KA, Rowe LB, Tipper DJ.J Biol Chem. 1977 Dec 25;252(24):9010-7.Virus-like particles containing the L (P1)-species of double-stranded RNA (dsRNA) were isolated from Saccharomyces cerevisiae, and the translational activity of the virus-like particle-derived dsRNA was analyzed in the wheat germ cell-free system. Denaturation of the dsRNA immediately prior to in vitro translation resulted in the synthesis of one major and at least three minor polypeptides, whereas undenatured dsRNA, as expected, did not stimulate [35S]methionine incorporation into polypeptides, but actually slightly inhibited endogenous activity. The major in vitro translation product of the denatured L-dsRNA was shown to be identical with the major L-dsRNA containing virus-like particle capsid polypeptide on the basis of three criteria: co-electrophoresis on sodium dodecyl sulfate polyacrylamide gels, immunoprecipitation, and tryptic peptide analysis. We have therefore established that the L-dsRNA genome encodes the major virus-like particle capsid polypeptide. This result adds considerable support to the hypothesis that the L-dsRNA genome acts as a helper genome to the smaller (1.6 x 10(6) dalton) M-dsRNA genome in killer strains of yeast by providing the M-dsRNA containing virus-like particles with their major coat protein.