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- JournalDigital Access ScienceDirect v. 1-, 2014-
- ArticleHazout S, Valleron AJ.Cell Tissue Kinet. 1977 Nov;10(6):569-74.Suicide experiments involve a great degree of uncertainty in the counting of cell colonies. This work studies from a statistical point of view the precision of the estimation as a function of the number of experimental units which are used. Assuming that the colony numbers in recipients follow a Poisson distribution, we give the necessary number of recipients (a) to determine with a given accuracy the percentage of DNA synthesizing cells (S cells), (b) to test whether or not a cell population is quiescent, and (c) to compare the percentages of S cells in two cell populations.