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- BookCharlotte Sweeney and Fleur Bothwick.Contents:
About the authors
Acknowledgements
Foreword from larry hirst cbe
Introduction
Starting out
What is "starting out"?
Assessing your current position
Creating the case for change
Building a strategic plan
Your role as a change agent
Who is there to help? : working with external providers
Taking the leap
Building your team
Communicating the change
Bias and unconscious bias training
Talent management : recruitment to career development
Talent management : reward to exit
Networks
Achieving change
Inclusive leadership development
New ways of working
Removing barriers and obstacles
Thinking global, acting local
Reaping the rewards
Measuring impact and realising the benefits
Embedding your strategy into the culture
Leveraging d & i in the market
Looking forward
Conclusion
References.PrintLocationVersionCall NumberItems - ArticleFujimoto S.Nihon Yakurigaku Zasshi. 1977 Apr;73(3):257-66.Production, transport, storage and release of antidiuretic hormone (ADH) in the hypothalamo-neurohypophysial system were investigated. ADH produced by nerve cells in the paraventricular and supraoptic nuclei of the hypothalamus is present in a form bound to the specific protein neurophysin, in the neurosecretary granula. Electric and chemical stimulation of these nuclei results in evoked release of ADH in ionic association with neurophysin from the neural lobes. Acetylcholine, norepinephrine, histamine, angiotensin II, gamma-aminobutyric acid and L-glutamic acid have been regarded as candidates of chemical transmitters for the release of ADH in the hypothalamus. Prostaglandin (PG) E2 may be another important compound for central regulation of water metabolism. The possibility that PGE2 may be the transmitter or a modulator in the nuclei has to be considred. Serotonin, dopamine and taurine, however, may not be involded in the ADH releasing mechanisms in the hypothalamus. It appears that norepinephrine, histamine, angiotensin II, PGE2 and bradykinin stimulate directly the neural lobe to release ADH. The ADH release is regulated by intracellular Ca++. The existence of a "readily-releasable pool" of ADH can be ruled out and any limitation in the amount of ADH released under experimental conditions may be due to insufficient activation of the neural lobe. A physiological significance other than a carrier was proposed for neurophysin.