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  • Book
    Charlotte Sweeney and Fleur Bothwick.
    Contents:
    About the authors
    Acknowledgements
    Foreword from larry hirst cbe
    Introduction
    Starting out
    What is "starting out"?
    Assessing your current position
    Creating the case for change
    Building a strategic plan
    Your role as a change agent
    Who is there to help? : working with external providers
    Taking the leap
    Building your team
    Communicating the change
    Bias and unconscious bias training
    Talent management : recruitment to career development
    Talent management : reward to exit
    Networks
    Achieving change
    Inclusive leadership development
    New ways of working
    Removing barriers and obstacles
    Thinking global, acting local
    Reaping the rewards
    Measuring impact and realising the benefits
    Embedding your strategy into the culture
    Leveraging d & i in the market
    Looking forward
    Conclusion
    References.
    Print
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    HD57.7 .S94 2016
    1
  • Article
    Fujimoto S.
    Nihon Yakurigaku Zasshi. 1977 Apr;73(3):257-66.
    Production, transport, storage and release of antidiuretic hormone (ADH) in the hypothalamo-neurohypophysial system were investigated. ADH produced by nerve cells in the paraventricular and supraoptic nuclei of the hypothalamus is present in a form bound to the specific protein neurophysin, in the neurosecretary granula. Electric and chemical stimulation of these nuclei results in evoked release of ADH in ionic association with neurophysin from the neural lobes. Acetylcholine, norepinephrine, histamine, angiotensin II, gamma-aminobutyric acid and L-glutamic acid have been regarded as candidates of chemical transmitters for the release of ADH in the hypothalamus. Prostaglandin (PG) E2 may be another important compound for central regulation of water metabolism. The possibility that PGE2 may be the transmitter or a modulator in the nuclei has to be considred. Serotonin, dopamine and taurine, however, may not be involded in the ADH releasing mechanisms in the hypothalamus. It appears that norepinephrine, histamine, angiotensin II, PGE2 and bradykinin stimulate directly the neural lobe to release ADH. The ADH release is regulated by intracellular Ca++. The existence of a "readily-releasable pool" of ADH can be ruled out and any limitation in the amount of ADH released under experimental conditions may be due to insufficient activation of the neural lobe. A physiological significance other than a carrier was proposed for neurophysin.
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