Bookedited by David Robertson, Gordon H. Williams.
Contents:
Section I Fundamental Principles
1. Introduction to clinical research / Gordon H. Williams and David Robertson
2. Patient-oriented research / Ellen W. Seely and Steven Grinspoon
3. Clinical trials / Robert M. Califf
4. Introduction to epidemiology / Donna K. Arnett and Steven A. Claas
5. The patient-centered outcomes research institute / Joe V. Selby and Danielle M. Whicher
6. Health-care technology assessment (HTA) / Uwe E. Reinhardt
7. Health services research / J. Sanford Schwartz
Section II Approaches
8. Measurement of biological materials / Mark D. Kellogg
9. Imaging tools in clinical research / Ruth M. Dunne, Alibhe C. O'Neill and Clare M. Tempany
10. Imaging tools in human research / Ruth M. Dunne, Alibhe C. O'Neill and Clare M. Tempany
11. Nanotechnology in clinical and translational research / James B. Baker Jr., Brent B. Ward and Thommey P. Thomas
12. The use of questionnaires and surveys / Marcia A. Testa and Donald C. Simonson
13. Informational technology / Shawn N. Murphy, Henry C. Chueh and Christopher D. Herrick
14. Principles of biostatistics / Kush Kapur
15. Good clinical practice and good laboratory practice / Nathalie K. Zgheib, Stephanie L. Tomasic and Robert A. Branch
Section III Human Genetics
Introduction to human genetics / Bruce R. Korf
17. Epidemiologic and population genetic studies / Angela J. Rogers and Scott T. Weiss
18. Pharmacogenetics of drug metabolism / Zerusenay Desta and David A. Flockhart
19. Statistical techniques for genetic analysis / Jessica Lasky-Su
Section IV Human Pharmacology
20. Introduction to clinical pharmacology / Rommel G. Tirona and Richard B. Kim
21. Adverse drug events / Dan M. Roden
Section V Societal Context of Human Research
22. Translating science to the bedside / Seema Basu
23. Regulatory environment / Christine Nguyen, Audrey Gassman and Hylton V. Joffe
24. Ethical issues in translational research and clinical investigation / Greg Koski
25. Clinical research in the public eye / Mary Wooley
Section VI Research in Special Populations
26. Research in special populations / Todd W. Rice and Gordon R. Bernard
27. Research in the emergency care environment / James Quinn and Daniel J. Pallin
28. Psychiatric disorders / Alan F. Schatzberg
29. Research in special populations / Stephanie Studenski and Luigi Ferrucci
30. Clinical research in neurology / Keren Regev and Howard L. Weiner
31. Research in pediatrics / Lisa Bomgaars, Stacey Berg and Ann R. Stark
32. Cancer as a paradigm for translational and clinical biomedical research / César Serrano and George D. Demetri
33. Maintaining an emphasis on rare diseases with research initiatives and resources at the national center for advancing translational sciences / Stephen C. Groft and Rashmi Gopal-Srivastava
Section VII Infrastructure
34. Clinical and Translational Science Infrastructure / David Robertson and Gordon H. Williams
Section VIII Education, Training and Career Choices
35. Education, Training and Career Choices / Katherine E. Hartmann, Elizabeth Heitman and Nancy J. Brown
A stepwise approach to a career in translational research / William F. Crowley Jr.
Physician careers in the pharmaceutical industry / Ronald L. Krall
Section IX Research in Academia
38. Industry-sponsored clinical research in academia / Italo Biaggioni
39. Governmental support of research / Sten H. Vermund and Salim Abdool Karim
40. The role of nonprofit, non-governmental funding in support of biomedical research / Rose Marie Robertson and Suzie Upton
41. Modern drug discovery and development / Daniel E. Salazar and Glenn Gormley
42. Pharmaceutical and biotechnology sector support of research / Joann Data
Section X Prospectus
43. The future of clinical research / Gordon H. Williams and David Robertson.