Live Chat
Today's Hours: 8:00am - 10:00pm
Lane Medical Library

Search

Filter Results

Did You Mean:

Search Results

Sort by
relevance
  • Book
    volume editor, Peter Vogt.
    Contents:
    Genetic basis of male and female infertility / R. Mallepaly, P.R. Butler, A.S. Herati, D.J. Lamb
    Genetics of premature ovarian failure : new developments in etiology opportunity / Y. Qin, J.L. Simpson, Z.-J. Chen
    Genetics of Klinefelter syndrome : experimental exploration / J. Wistuba, C. Brand, M. Zitzmann, O.S. Damm
    Human Y chromosome and male infertility : forward and back from azoospermia factor chromatin structure to azoospermia factor gene function / P.H. Vogt, U. Bender, J. Zimmer, T. Strowitzki
    Genetics and pathophysiology of the cystic fibrosis transmembrane conductance regulator in male reproduction : new evidence of a direct effect on the male germline / A. Touré
    The genetics of androgen receptor signalling in male fertility / L. O'Hara, L.B. Smith
    The genetics of postmeiotic male germ cell differentiation from round spermatids to mature sperm / T. Lehtiniemi, N. Kotaja
    The epigenetics of sperm chromatin / M.B. Shamsi, L. Simon, D.T. Carrell
    Characteristic features of male germline development in primates / R. Behr
    Genetic and epigenetic mouse models of human male infertility / M. Godmann, S. Zemter, C. Kosan
    In vitro spermatogenesis and its potential clinical implication for patients / J.-B. Stukenborg, K. Jahnukainen.
    Digital Access Karger 2017
  • Article
    Williams RH, Thomas C, Bell D, Navar LG.
    Am J Physiol. 1977 Oct;233(4):F282-9.
    Micropuncture studies were conducted in anesthetized dogs to evaluate single nephron glomerular filtrate rate (SNGFR) and SNGFR autoregulation when assessed by means of an indicator-dilution technique (SNGFRID), which does not require interruption of distal volume delivery. In 18 dogs, control renal arterial pressure was 124 +/- 11 mmHg (SD), renal blood flow (RBF) was 185 +/- 58 ml/min, and whole kidney GRF was 37 +/- 7 ml/min. SNGFRID averaged 57 +/- 15 nl/min and was significantly lower than SNGFR determined on the basis of total collections (SNGFRTC) from proximal tubules (75 +/- 17 nl/min). However, SNGFRID was not significantly different from the overall average SNGFR of 62 +/- 12 nl/min estimated from whole kidney GFR and the total number of glomeruli (613,000 +/- 74,000). In 10 animals, renal arterial pressure was reduced to an average of 94 +/- 8 mmHg; whole kidney autoregulation was highly efficient and average RBF and GRF remained within 1 and 3% of their control values. Likewise, SNGFRID was not significantly altered at 52 +/- 17 and 52 +/- 16 nl/min. In contrast, SNGFRTC decreased significantly from 72 +/- 17 to 51 +/- 13 nl/min. These results indicate that the indicator-dilution technique provides a reliable assessment of SNGFR and allows the manifestation of single nephron autoregulatory behavior. They provide further support for the hypothesis that maintenance of distal volume delivery may be a necessary aspect of the autoregulation phenomenon.
    Digital Access Access Options