Bookedited by Nicholas Boulis, Deirdre O'Connor, and Anthony Donsante.
Contents:
1. Molecular and extracellular cues in motor neuron specification and differentiation / R.L. Swetenburg, S.L. Stice and L. Karumbaiah
2. Natural history of amyotrophic lateral sclerosis / M.J. Magnussen and J.D. Glass
3. Genetics of amyotrophic lateral sclerosis / K.P. Kenna, J.E. Landers and N. Ticozzi
4. Molecular mechanisms of amytrophic lateral sclerosis / M. Collins and R. Bowser
5. An introduction to natural history, genetic mapping, and clinical spectrum of spinal muscular atrophy / A. McDonough, L. Urquia and N. Boulis
6. Genetics of spinal muscular atrophy / A.H.M. Burghes and V.L. McGovern
7. Introduction to gene and stem-cell therapy / D.M. O'Connor
8. Gene therapy for amytrophic lateral sclerosis / A. Dosante
9. Stem cell therapy for amytrophic lateral sclerosis / K.S. Chen and E.L. Feldman
10. Gene therapy for spinal muscular atrophy / M.R. Miller, E.Y. Osman and C.L. Lorson
11. Cellular therapy for spinal muscular atrophy / I. Faravelli and S. Corti
12. Clinical trials to date / B.J. Mader and N. Boulis.