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- Bookedited by Surendra Nimesh, Ramesh Chandra, Nidhi Gupta.Contents:
1. Nanomedicine for delivery of therapeutic molecules
2. Nanoparticles as nucleic acid delivery vectors
3. Methods for charactericzation of nanoparticles
4. Nanoparticles for DNA delivery
5. Nanoparticles for siRNA-mediated gene silencing
6. Nanoparticles for locked nucleic acid delivery
7. Nanoparticles for ribozymes delivery
8. Nanoparticles for DNAzymes delivery
9. Pharmacokinetics and biodistribution of the nanoparticles
10. Nanotoxicology: evaluation of toxicity potential of nanoparticles
11. Regulatory aspects of nanoparticulate mediated nucleic acid delivery systems
12. Clinical studies and future prospects
Index.Digital Access ScienceDirect 2017 - ArticleAsaba H, Bergström J, Fürst P, Gordon A, Groth CG, Oules R, Zimmerman L.Clin Nephrol. 1977 Aug;8(2):329-34.The plasma level and urinary excretion of middle molecules were determined in 5 patients with chronic uremia undergoing renal transplantation. The results demonstrate that after successful transplantation, the uremic middle molecules disappear rapidly from plasma while being excreted in the urine. The reduction in plasma level of middle molecules after transplantation is more rapid than the reduction in creatinine concentration.