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  • Book
    edited by Ibrahim Abubakar, Helen R. Stagg, Ted Cohen, and Laura C. Rodrigues.
    Summary: This volume provides a concise reference for practicing epidemiologists, and provides trainee readers with a thorough understanding of basic the concepts which are critical to understanding specialist areas of infectious disease epidemiology.
    Digital Access Oxford 2016
  • Article
    Morrisett JD, Jackson RL, Gotto AM.
    Biochim Biophys Acta. 1977 Aug 09;472(2):93-133.
    The purpose of this review has been to discuss new information about the mechanism of lipid and apoprotein interaction in the plasma lipoproteins. A special form of the amphipathic helix has been identified as a major structural element of the apolipoproteins sequenced to date. Evidence is reviewed concerning the role of the amphipathic helix in the binding to phospholipids. Several different models for the organization of the components of HDL, LDL and LP-X have evolved from extensive structural studies. Resolution of the differences among these models will require additional experimental testing. Verification of models based on the study of reconstituted HDL will require rigorous proof of native structure in these particles. A detailed description of the molecular organization of the lipid and protein constituents of the plasma lipoproteins is still lacking. Further structural and sequence studies with apoB and the "arginine-rich" protein are needed. Crystallization of an apoprotein or lipoprotein and determination of the three-dimensional structure would be a major achievement. With such further detailed structural information, it may then be possible to correlate changes in structure with determinants of metabolism.
    Digital Access Access Options