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  • Book
    edited by Charles L. Edelstein.
    Contents:
    Chapter 1: Characteristics of an Ideal Biomarker of Kidney Diseases / M.R Bennett aand P. Devarajan
    Chapter 2: Statistical Considerations in Analysis and Interpretation of Biomarker Studies / C.R. Parikh and H. Theissen Philbrook
    Chapter 3: The Role of Metabolomics in the Study of Kidney Diseases and in the Development of Diagnostic Tools / U. Christians, J. Klawitter, J. Klepacki and J. Klawitter
    Chapter 4: The Role of Proteomics in the Study of Kidney Diseases and in the Development of Diagnostic Tools / U. Christians, J. Klawitter, J. Klepacki and J. Klawitter
    Chapter 5: Cystatin C as a Multifaceted Biomarker in Kidney Disease and Its Role in Defining "Shrunken Pore Syndrome" / A. Grubb
    Chapter 6: Biomarkers in Acute Kidney Injury / C.L. Edelstein
    Chapter 7: Biomarkers of Extra-Renal Complications of AKI / S. Faubel
    Chapter 8: Biomarkers in Kidney Transplantation / S. Jain and A. Jani
    Chapter 9: Biomarkers of Renal Cancer / N.S. Vasudev and R.E. Banks
    Chapter 10: Proteomics and Advancements in Urinary Biomarkers of Diabetics Kidney Disease / M.L. Merchant and J.B. Klein
    Chapter 11: Biomarkers of Cardiovascular Risk in Chronic Kidney Disease / Z.H. Endre and R.J. Walker
    Chapter 12: Diagnostic and Prognostic Biomarkers in Autosomal Dominant Polycystic Kidney Disease / G. Fick-Brosnahan and B.Y. Reed
    Chapter 13: Biomarkers in Glomerular Disease / J.M. Arthur, E. Elnagar and N. Karakala
    Chapter 14: Biomarkers in Preeclampsia / S.A. Karamanchi.
    Digital Access ClinicalKey 2017
  • Article
    Redman CW, Beilin LJ, Bonnar J.
    Br J Obstet Gynaecol. 1977 Jun;84(6):419-26.
    A total of 242 women with moderate hypertension in pregnancy completed a controlled trial of methyldopa (Aldomet). The hypotensive effect of methyldopa was similar to its action in non-pregnant individuals and greatly reduced the frequency of severe hypertension occurring antenatally and in labour. As pregnancy advanced, an increasing daily dose of methyldopa was needed and there was a greater use of additional hypotensive therapy. Seventeen (14-5 per cent) women assigned to methyldopa had to be transferred to another drug or had to stop treatment completely because of minor side effects, of which the commonest were lack of energy and dizziness. No serious side effects were encountered. Nine per cent of the untreated women developed severe hypertension which required treatment later in their pregnancies. Six weeks after delivery, nearly all the patients were able to stop treatment.
    Digital Access Access Options