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  • Book
    Ji Y. Chong, Michael P. Lerario.
    Contents:
    1. Treatment of acute right-sided weakness
    2. Large vessel occlusion
    3. Masquerade
    4. Improving symptoms
    5. Progressive quadriplegia
    6. Malignant edema
    7. To treat or not to treat (blood pressure)
    8. Unidentified bright objects
    9. Detected bruit
    10. Small vessel disease
    11. Obstructed flow
    12. Aphasia and atherosclerosis
    13. A new arrhythmia
    14. Arch disease
    15. Hole in my heart
    16. Investigating the occult
    17. A Horner's syndrome following trauma
    18. Young adult with headache and blurred vision
    19. Cancer and coagulopathy
    20. Fevers in a patient with valve replacement
    21. Seeing jellyfish
    22. Driving is a headache
    23. Puff of smoke
    24. Thunderclap headache
    25. Hypertension and confusion
    26. A protean presentation
    27. Can I go home now?
    28. Cardiac arrest
    29. A sickle pickle
    30. Numbness while on anticoagulation
    31. Hemorrhage in a patient with dementia
    32. An unusual hemorrhage
    33. Recurrent headaches
    34. Progressive gait dysfunction
    35. Worst headache of her life
    36. An incidental finding
    37. Forget about it
    38. Seizures, sadness, and spasticity.
    Digital Access Oxford 2017
  • Article
    Hewitt HB, Blake ER.
    Br J Cancer. 1977 Jul;36(1):23-34.
    Of 193 CBA mice kept under prolonged observation after excision of small intradermal transplants of a non-immunogenic tumour (CBA Carcinoma NT), 27 (14%) presented with local recurrence, 19 (10%) with regional lymphnodal metastasis (RNM) and 72 (37%), with pulmonary metastasis +/- other systemic metastases. When mice were exposed to sublethal whole-body irradiation (WBI) before tumour transplantation, the incidence of RNM rose to approximately 80% and the latent period was reduced from approximately 60 days to approximately 40 days after tumour transplantation. This enhancement of RNM by WBI was undiminished when the interval between WBI and tumour transplantation was increased from 1 to 90 days. An explanation for this effect in terms of immunosuppression by the WBI is unlikely for the following reasons: the tumour was non-immunogenic by standard quantitative tests; the effect persisted long after the expected time for recovery of immune reactivity; and i.v. injection of normal marrow and lymphoid cells after WBI failed to reduce the effect. That the effect was systemic was proved by failure of local pre-irradiation of the tumour bed or regional node to enhance RNM. The effect was not observed when WBI was given 4 days after excision of tumours. These and other experiments failed to indicate the mechanism of the effect of WBI, but its long persistence suggests that it may relate to stored lethal radiation damage in migrating cells of slow turnover tissues.
    Digital Access Access Options
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