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- BookThokozani Majozi, E R Seid, and J-Y Lee.Contents:
Chapter 1. Introduction to batch processes
Chapter 2. Modelling for effective solutions: reduction of binary variables
Chapter 3. Methods to reduce computational time: prediction of time points
Chapter 4. Integration of scheduling and heat integration: minimization of energy requirements
Chapter 5. Heat integration in multipurpose batch plants
Chapter 6. Design and synthesis of heat-integrated batch plants using an effective technique
Chapter 7. Simultaneous scheduling and water optimization: reduction of effluent in batch facilities
Chapter 8. Optimization of energy and water use in multipurpose batch plants using an improved mathematical formulation
Chapter 9. Targeting for long-term horizons: water optimization
Chapter 10. Long-term heat integration in multipurpose batch plants using heat storage
Index.Digital Access TandFonline 2017 - ArticleSites in nucleic acids reacting with alkylating agents of differing carcinogenicity of mutagenicity.Singer B.J Toxicol Environ Health. 1977 Jul;2(6):1279-95.The site of alkylation of a nucleic acid, in vivo, is greatly dependent on the type of alkylating agent. Most alkylating agents of low mutagenicity or carcinogenicity (such as dimethylsulfate) react primarily with the ring nitrogens. The carcinogenic N-nitroso compounds have a great affinity for alkylating oxygens and react with all ring oxygens as well as the phosphodiesters and, in the case of RNA, with the 2'-O of ribose. Ethylating agents, though in absolute terms less reactive than the corresponding methylating agents, show even greater affinity toward oxygens. It appears that the ethyl nitroso compounds that are carcinogenic are also the most reactive with oxygens.