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  • Book
    Lang Tran, Miguel A. Bañares, Robert Rallo, editors.
    Summary: In today's nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios. Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in risk assessment. Specific topics include the physico-chemical characteristics of engineered nanoparticles, nanoparticle interactions, in vivo nanoparticle processing, and more. A much-needed practical guide, Modelling the Toxicity of Nanoparticles is a key text for researchers as well as government and industry regulators.

    Contents:
    Engineering nanomaterials: their physicochemical characteristics and how to measure them
    Assessment of human exposure to ENMs
    The life cycle of engineered nanoparticles
    From dose to response: in vivo nanoparticle processing and potential toxicity
    Literature review of (Q)SAR modelling of nanomaterial toxicity
    Systems biology to support nanomaterial grouping
    Multiscale modelling of bionano interface
    Biological surface adsorption index of nanomaterials: modelling surface interactions of nanomaterials with biomolecules
    An integrated data-driven strategy for safe-by-design nanoparticles: the FP7 MODERN project
    Compilation of data and modelling of nanoparticle interactions and toxicity in the NanoPUZZLES project
    Case study III: the construction of a nanotoxicity database, the MOD-ENP-TOX experience.
    Digital Access Springer 2017
    Access via Advances in experimental medicine and biology ; 2017; 947
    Location
    Version
    Call Number
    Items
    Advances in experimental medicine and biology ; 2017; 947
    2017
  • Article
    Compton FH, Beagrie GS, Chernecky R.
    J Periodontol. 1977 Jul;48(7):418-20.
    Six systems (one polycarboxylate, one polymethyl methacrylate, one unfilled BIS-GMA resin, two combinations of methyl cyanoacrylate and polymethyl methacrylate, and one combination of unfilled BIS-GMA and filled composite resin) were evaluated for in vitro retention to acid-etched human enamel. Also tested were one unfilled-filled resin combination backed by perforated orthodontic band metal and another unfilled resin backed by stainless steel wire mesh. Significant differences in retention were found. Results show that retention depends pril surface and to resist subsequent chemical degradation.
    Digital Access Access Options