Bookedited by Cheng Liu, K. John Morrow Jr.
Contents:
The history of therapeutic monoclonal antibodies / Regis Sodoyer
Structure, classification and naming of therapeutic monoclonal antibodies / Zhinan Xia
Mechanism of action for therapeutic antibodies / Yu Zhou and James D. Marks
Therapeutic monoclonal antibodies and their targets / Maurizio Chiriva-Internati, et al
Antibody post-translational modifications / Roy Jefferis
The pharmacology, pharmacokinetics, and pharmacodynamics of antibodies / Ningning Xu, Meimei Liu, Margaret Liu
Monoclonal antibodies : applications in clinical oncology / Jeanene ("Gigi") Robison
Development of biosimilar rituximab and clinical experience / Reena Nair
Monoclonal antibodies for infectious diseases / Steven J. Projan
Monoclonal antibodies for musculoskeletal, CNS, and other diseases / Junming Yie and Tao Wu
Manufacture of recombinant therapeutic proteins using chinese hamster ovary cells in large-scale bioreactors : history, methods and perspectives / Florian M. Wurm and Maria De Jesus
Process development / Samuel D. Stimple and David W. Wood
Biosimilars and biobetters : impact on biopharmaceutical manufacturing and CMOs / Ronald A. Rader
Cell line and cell culture development for biosimilar antibody drug manufacturing / Jianguo Yang
Product analysis of biosimilar antibodies / Weidong Jiang, Scott Liu and Ziyang Zhong
Bioanalytical development / Rafiq Islam
Preclinical and clinical development of biosimilar antibodies / João Eurico Fonseca and João Gonçalves
Regulatory issues / Clarinda Islam
Legal considerations / K. Lance Anderson, Jennifer R. Moore Meline, and Jonathan D. Ball
ADCC enhancement technologies for next generation therapeutic antibodies / Cheng Liu and Su Yan
Biosimilar antibody half-life : engineering for optimal performance / K. John Morrow, Jr
Technologies for antibody drug conjugation / Patrick G. Holder and David Rabuka.