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  • Book
    J. Robin Harris, Jon Marles-Wright, editors.
    Contents:
    Structure and function of the stressosome signalling hub / Jan Pané-Farré, Maureen B. Quin, Richard J. Lewis, Jon Marles-Wright
    The canonical inflammasome: a macromolecular complex driving inflammation / Tom P. Monie
    The Ferritin Superfamily / Alejandro Yévenes
    Antibody recognition of immunodominant vaccinia virus envelope proteins / Dirk M. Zajonc
    The peroxiredoxin family: an unfolding story / Zhenbo Cao, John Gordon Lindsay
    [alpha]2-Macroglobulins: structure and function / Irene Garcia-Ferrer, Aniebrys Marrero, F. Xavier Gomis-Rüth, Theodoros Goulas
    The Structure and Function of the PRMT5:MEP50 complex / Stephen Antonysamy
    Symmetry-directed design of protein cages and protein lattices and their applications / Aaron Sciore, E. Neil G. Marsh
    Structure and function of RNA polymerases and the transcription machineries / Joachim Griesenbeck, Herbert Tschochner, Dina Grohmann
    Dihydrodipicolinate synthase: structure, dynamics, function, and evolution / F. Grant Pearce, André O. Hudson, Kerry Loomes, Renwick C. J. Dobson
    Pyruvate carboxylase, structure and function / Mikel Valle
    Cullin-RING E3 ubiquitin ligases: bridges to destruction / Henry C. Nguyen, Wei Wang, Yong Xiong
    The Ccr4-Not complex: architecture and structural insights / Martine A. Collart, Olesya O. Panasenko
    Higher-order structure in bacterial VapBC toxin-antitoxin complexes / Kirstine L. Bendtsen, Ditlev E. Brodersen
    D-glyceraldehyde-3-phosphate dehydrogenase structure and function / Michael R. White, Elsa D. Garcin
    Protein complexes in the nucleus: the control of chromosome segregation / Victor M. Bolanos-Garcia
    GroEL and the GroEL-GroES complex / Noriyuki Ishii
    The aminoacyl-tRNA synthetase complex / Marc Mirande
    The pyruvate dehydrogenase complex and related assemblies in health and disease / Olwyn Byron, John Gordon Lindsay
    Structure and assembly of clathrin cages / Mary Halebian, Kyle Morris, Corinne Smith.
    Digital Access ProQuest Ebook Central 2017
    Limited to 3 simultaneous users
  • Article
    van der Schans GS, Veenhoven WA, Snijder JA, Nieweg HO.
    J Lab Clin Med. 1977 Jul;90(1):4-10.
    A membrane ummunofluorescence test for the detection of platelet isoantibodies is described. Gel filtration of the incubation mixture was incorporated in the procedure and proved effective for the removal of serum proteins from the platelet suspension. With this technique isoantibodies were found in the serum of 13 out of a group of 16 patients who had received multiple transfusions. The results were checked by measuring the uptake of 125I-labeled anti-IgG fraction by gel-filtered platelets. Subsequently the membrane immunofluorescence method was also compared with established techniques described for the detection of isoantibodies such as the microtest for lymphocytotoxicity and a complement-fixation method and the procedures based on the release of labeled serotonin, the phagocytosis of chromium-tagged platelets, the increase of platelet factor 3 activity, and on platelet aggregation. We had the opportunity to investigate the serum of one patient for the presence of isoantibodies against platelets from HLA identical siblings both before and after the administration of their platelets. On the basis of this experience it is concluded that the membrane immunofluorescence test for platelet isoantibodies is a relatively simple method with a high degree of specificity and adequate sensitivity.
    Digital Access Access Options