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  • Book
    Francisco Pelegri, Michael Danilchik, Ann Sutherland, editors.
    Summary: "This book provides a comprehensive overview of topics describing the earliest steps of fertilization, from egg activation and fertilization to the activation of the zygotic genome, in various studied vertebrate model systems. The contribution of maternal and paternal factors and their role in the early embryo as parental DNA becomes modified and embryonic genes become activated is fundamental to the initiation of embryogenesis in all animal systems. It can be argued that this is a unique developmental period, when information from the parents is compressed to direct the development of the body plan of the entire organism, a process of astounding simplicity, elegance and beauty. In addition to their fundamental scientific interest, many frontiers of biomedicine, such as reproductive biology, stem cells and reprogramming, and the understanding of intergenerational diseases, depend on advances in our knowledge of these early processes. Vertebrate Development: Maternal to Zygotic Control brings together chapters from experts in various disciplines describing the latest advances related to this important developmental transition. Each chapter is a synthesis of knowledge relevant to all vertebrates, with details on specific systems as well as comparisons between the various studied vertebrate models. The editorial expertise encompasses the fields of major vertebrate model systems (mammalian, amphibian and teleost) ensuring a balanced approach to various topics. This unique book&with its combination of in-depth and up-to-date basic research, inter-species comprehensiveness and emphasis on the very early stages of animal development&is essential for research scientists studying vertebrate development, as well as being a valuable resource for college educators teaching advanced courses in developmental biology"--Publisher's description.

    Contents:
    Egg activation at fertilization / Zoltan Machaty, Andrew R. Miller, Lu Zhang
    Controlling the messenger: regulated translation of maternal mRNAs in Xenopus laevis development / Michael D. Sheets, Catherine A. Fox, Megan E. Dowdle, Susanne Imboden Blaser [and others]
    Regulation of cell division / Andreas Heim, Beata Rymarczyk, Saurav Malhotra, Thomas U. Mayer
    Vertebrate embryonic cleavage pattern determination / Andrew Hasley, Shawn Chavez, Michael Danilchik, Martin Wühr, Francisco Pelegri
    Localization in oogenesis of maternal regulators of embryonic development / Matias Escobar-Aguirre, Yaniv M. Elkouby, Mary C. Mullins
    Vertebrate axial patterning: from egg to asymmetry / Douglas W. Houston
    Establishment of the vertebrate germ layers / Wei-Chia Tseng, Mumingjiang Munisha, Juan B. Gutierrez, Scott T. Dougan
    Mechanisms of vertebrate germ cell determination / Tristan Aguero, Susannah Kassmer, Ramiro Alberio, Andrew Johnson, Mary Lou King
    Cell cycle remodeling and zygotic gene activation at the midblastula transition / Maomao Zhang, Jennifer Skirkanich, Michael A. Lampson, Peter S. Klein
    Clearance of parental products / Petr Svoboda, Helena Fulka, Radek Malik.
    Digital Access Springer 2017
  • Article
    Burman LG.
    J Bacteriol. 1977 Jul;131(1):69-75.
    The normal habitat of enteric bacteria is largely anaerobic. Expression of the three characteristic properties of R-plasmids, drug resistance, vegetative replication, and fertility, was therefore studied in Escherichia coli K-12 during anaerobiosis. Replication and drug resistance functions were not altered in the 45 R-plasmids studies, whereas the expression of fertility varied considerably among different R-plasmids during anaerobiosis. The R-plasmids could be divided into three groups, one showing a strong, the second a moderate, and the third little or no reduction of fertility by anaerobiosis. Plasmid-determined sensitivity to F-, N-, and I-specific phage, respectively, was well, although not absolutely, correlated with each of three groups mentioned. Anaerobiosis-aerobiosis appears to change the fertility of type F R-plasmids by influencing the degree of repression of their fertility functions such as the formation of sex pili. Although the minimum inhibitory concentrations of ampicillin, chloramphenicol, streptomycin, and tetracycline were unaltered by anaerobiosis, sulfonamide was found to be four- to eightfold less active under this condition in both resistant and sensitive strains. A surprisingly high frequency and uniformity of minimal inhibitory concentrations was observed for R-plasmid-mediated resistance to streptomycin and chloramphenicol.
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